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The elongation and membrane targeting stages of eukaryotic translation. The ribosome is green and yellow, the tRNAs are dark-blue, and the other proteins involved are light-blue. Elongation depends on eukaryotic elongation factors. At the end of the initiation step, the mRNA is positioned so that the next codon can be translated during the ...
In order to maintain a standard for Cell and molecular biology articles a standard color scheme should be used. The accepted colors for cellular locations are described in the table. Colors for other components, such as molecules, can be chosen at the discretion of the designer, however, the following should be considered:
The diagrams presented show how fatty acids are synthesized in microorganisms and list the enzymes found in Escherichia coli. [2] These reactions are performed by fatty acid synthase II (FASII), which in general contain multiple enzymes that act as one complex. FASII is present in prokaryotes, plants, fungi, and parasites, as well as in ...
Elongation is the most rapid step in translation. [3] In bacteria , it proceeds at a rate of 15 to 20 amino acids added per second (about 45-60 nucleotides per second). [ citation needed ] In eukaryotes the rate is about two amino acids per second (about 6 nucleotides read per second).
Basic reproduction number: number of infections caused on average by an infectious individual over entire infectious period: epidemiology: Body fat percentage: total mass of fat divided by total body mass, multiplied by 100: biology Kt/V: Kt/V: medicine (hemodialysis and peritoneal dialysis treatment; dimensionless time) Waist–hip ratio
In extreme cases, for example, when the polymerase encounters a damaged nucleotide, it comes to a complete halt. More often, an elongating polymerase is stalled near the promoter. [32] Promoter-proximal pausing during early elongation is a commonly used mechanism for regulating genes poised to be expressed rapidly or in a coordinated fashion.
Once translation initiation is complete, the first aminoacyl tRNA is located in the P/P site, ready for the elongation cycle described below. During translation elongation, tRNA first binds to the ribosome as part of a complex with elongation factor Tu or its eukaryotic or archaeal counterpart. This initial tRNA binding site is called the A/T site.
A clear example of an enzyme that follows this scheme is H+-transporting two-sector ATPase: ATP + H 2 O + 4 H + side 1 = ADP + phosphate + 4 H + side 2 A) ATP-ADP translocase: protein responsible for the 1: 1 exchange of intramitochondrial ATP for ADP produced in the cytoplasm. B) Phosphate translocase: the transport of H2PO4- together with a ...