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Guanfacine, sold under the brand name Tenex (immediate-release) and Intuniv (extended-release) among others, is an oral alpha-2a agonist medication used to treat attention deficit hyperactivity disorder (ADHD) and high blood pressure.
Guanabenz is used as an antihypertensive drug used in the treatment of high blood pressure (hypertension). [1] [2] The most common side effects during guanabenz therapy are dizziness, drowsiness, dry mouth, headache and weakness. [3] Guanabenz can make one drowsy or less alert, therefore driving or operating dangerous machinery is not recommended.
7 Possible errors in 'Drug Synthesis' section image. 2 comments. 8 Use of guanfacine as treatment in cases of hyperadrenergic PoTS. 1 comment. 9 TAAR1 activity. 1 ...
A sympatholytic (sympathoplegic) drug is a medication that opposes the downstream effects of postganglionic nerve firing in effector organs innervated by the sympathetic nervous system (SNS). [1] They are indicated for various functions; for example, they may be used as antihypertensives .
Oral administration of a liquid. In pharmacology and toxicology, a route of administration is the way by which a drug, fluid, poison, or other substance is taken into the body. [1] Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration ...
Pemoline has been used in the treatment of ADHD and narcolepsy. [2] [1] [5] It has also been used in the treatment of excessive daytime sleepiness. [8]The medication was typically used at doses of 18.75 to 112.5 mg once per day in the treatment of ADHD, with the effective dose for most people being in the range of 56.25 to 75 mg. [1] [2] The onset of action of pemoline is gradual and ...
The United Kingdom's National Institute for Health and Care Excellence (NICE) guidelines recommend the use of methadone or buprenorphine as first-line agents in the management of opioid use disorder. However, lofexidine is considered an acceptable alternative for people with mild or uncertain opioid dependence in need of short-term detoxification.
English: Synthesis of guanfacine from 2,6-dichlorophenylacetic acid methyl ester and guanidine as described in United States Patent 3,632,645 Substituted phenylacetyl derivatives of guanidine o-alkylisoureas s-alkylisothioureas and p-nitrobenzylisothiourea, John Bernard Bream, Redbourn, Herts, and Claude W. Picard