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  2. HLA-DQB1 - Wikipedia

    en.wikipedia.org/wiki/HLA-DQB1

    Celiac1 is a genetic name for DQB1, the HLA DQB1*0201, *0202, and *0302 encode genes that mediate the autoimmune coeliac disease. Homozygotes of DQB1*0201 have a higher risk of developing the celiac disease, relative to any other genetic locus. [10]

  3. Coeliac disease - Wikipedia

    en.wikipedia.org/wiki/Coeliac_disease

    Coeliac disease (British English) or celiac disease (American English) is a long-term autoimmune disorder, primarily affecting the small intestine, where individuals develop intolerance to gluten, present in foods such as wheat, rye and barley. [10]

  4. Fecal fat test - Wikipedia

    en.wikipedia.org/wiki/Fecal_fat_test

    celiac disease (in which the fat malabsorption in severe cases is due to inflammatory damage to the integrity of the intestinal lining) short bowel syndrome (in which much of the small intestine has had to be surgically removed and the remaining portion cannot completely absorb all of the fat). small bowel bacterial overgrowth syndrome

  5. Gluten-related disorders - Wikipedia

    en.wikipedia.org/wiki/Gluten-related_disorders

    The results of a 2017 study suggest that non-celiac gluten sensitivity may be a chronic disorder, as is the case with celiac disease. [ 42 ] For people with wheat allergy , the individual average is six years of gluten-free diet, excepting persons with anaphylaxis, for whom the diet is to be wheat-free for life.

  6. Anti-transglutaminase antibodies - Wikipedia

    en.wikipedia.org/wiki/Anti-transglutaminase...

    Most attention to anti-transglutaminase antibodies is given with respect to celiac disease. A recent study of children published in 2007 demonstrated that the level of ATA in correlates with the scalar Marsh score for the disease in the same patient. [9] High levels of ATA are found in almost all instances of celiac disease. [10]

  7. Anti-gliadin antibodies - Wikipedia

    en.wikipedia.org/wiki/Anti-gliadin_antibodies

    Anti-gliadin antibodies were one of the first serological markers for coeliac disease. Problematic with AGA is the typical sensitivity and specificity was about 85%. Gliadin peptides which are synthesized as the deamidated form have much higher sensitivity and specificity, creating 2 serological tests for CD that approach biopsy diagnostic in ...

  8. Gluten challenge test - Wikipedia

    en.wikipedia.org/wiki/Gluten_challenge_test

    For people eating a gluten-free diet who are unable to perform an oral gluten challenge, an alternative to identify a possible celiac disease is an in vitro gliadin challenge of small bowel biopsies, but this test is available only at selected specialized tertiary-care centers. [5]

  9. Duodenal lymphocytosis - Wikipedia

    en.wikipedia.org/wiki/Duodenal_lymphocytosis

    As antibody-negative coeliac disease is recognised, HLA status, persistence or progression of the duodenal IEL numbers following a gluten challenge, followed by symptomatic improvement on a gluten-free diet, has been used to be more certain about the diagnosis, which was made in 22% of one series of over 200 adult cases.