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The collecting duct system of the kidney consists of a series of tubules and ducts that physically connect nephrons to a minor calyx or directly to the renal pelvis.The collecting duct participates in electrolyte and fluid balance through reabsorption and excretion, processes regulated by the hormones aldosterone and vasopressin (antidiuretic hormone).
The collecting duct system begins in the renal cortex and extends deep into the medulla. As the urine travels down the collecting duct system, it passes by the medullary interstitium which has a high sodium concentration as a result of the loop of Henle's countercurrent multiplier system. [1]: 67
Collecting duct carcinoma in computed tomography. Collecting duct carcinoma (CDC) is a type of kidney cancer that originates in the papillary duct of the kidney. It is rare, accounting for 1-3% of all kidney cancers. [2] It is also recently described; a 2002 review found just 40 case reports worldwide. [3]
Part of the renal cortex, a medullary ray is a collection of renal tubules that drain into a single collecting duct. [ citation needed ] Renal histology is the study of the microscopic structure of the kidney.
The DCT is lined with simple cuboidal cells, the distal convoluted tubule cells, that are shorter than those of the proximal convoluted tubule (PCT). The lumen appears larger in the PCT than the DCT lumen because the PCT has a brush border (microvilli).
The collecting ducts descend again into the medulla and fuse to wider collecting ducts, which pass through the inner medulla. [ 68 ] [ 69 ] Based on the location of the renal corpuscle in the cortex, nephrons are classified into 3 types: superficial (closer to the renal capsule), midcortical (in the middle part of the cortex) and juxtamedullary ...
The formation of urine begins within the functional unit of the kidney, the nephrons. Urine then flows through the nephrons, through a system of converging tubules called collecting ducts. These collecting ducts then join together to form the minor calyces, followed by the major calyces that ultimately join the renal pelvis. From here, urine ...
Within the nephron of the kidney, the ascending limb of the loop of Henle is a segment of the heterogenous loop of Henle downstream of the descending limb, after the sharp bend of the loop. This part of the renal tubule is divided into a thin and thick ascending limb ; the thick portion is also known as the distal straight tubule , in contrast ...