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Letrozole, sold under the brand name Femara among others, is an aromatase inhibitor medication that is used in the treatment of breast cancer for post-menopausal women. [ 1 ] It was patented in 1986 and approved for medical use in 1996. [ 4 ]
Ovarian stimulation with the aromatase inhibitor letrozole has been proposed for ovulation induction in order to treat unexplained female infertility. In a multi-center study funded by the National Institute of Child Health and Development, ovarian stimulation with letrozole resulted in a significantly lower frequency of multiple gestation (i.e., twins or triplets) but also a lower frequency ...
[4] [6] Peak levels of anastrozole occur a median 3 hours after administration, but with a wide range of 2 to 12 hours. [2] [4] Steady-state levels of anastrozole are achieved within 7 to 10 days of continuous administration, with 3.5-fold accumulation. [3] [2] [4] However, maximal suppression of estradiol levels occurs within 3 or 4 days of ...
Exemestane is known chemically as 6-methylideneandrosta-1,4-diene-3,17-dione. Like the aromatase inhibitors formestane and atamestane , exemestane is a steroid that is structurally similar to 4-androstenedione, the natural substrate of aromatase.
Reduced affect display, sometimes referred to as emotional blunting or emotional numbing, is a condition of reduced emotional reactivity in an individual. It manifests as a failure to express feelings either verbally or nonverbally, especially when talking about issues that would normally be expected to engage emotions.
In adolescents, emotional dysregulation is a risk factor for many mental health disorders including depressive disorders, anxiety disorders, post-traumatic stress disorder, bipolar disorder, borderline personality disorder, substance use disorder, alcohol use disorder, eating disorders, oppositional defiant disorder, and disruptive mood ...
3 Howard Goldman, a psychiatrist and public health expert the University of Maryland, cites another key advantage of the ACA: By allowing young adults to stay on their parents' plans, the law preserves access to psychiatric care right at the moment some will be first developing psychosis.
GameSpot gave the game 4.9/10 (Poor), stating that "Mind Quiz: Your Brain Coach is a shameless clone of Nintendo's brain-training DS game, Brain Age" and that "This game isn't good enough to serve as a game for Brain Age players who are looking for more of the same because it's too similar yet too shallow to entertain that crowd. If you fall ...