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Statins are usually used to lower blood cholesterol levels and reduce risk for illnesses related to atherosclerosis, with a varying degree of effect depending on underlying risk factors and history of cardiovascular disease. [16]
memory loss or forgetfulness; confusion; The following rare side effects are more serious. Like all statins, rosuvastatin can possibly cause myopathy, rhabdomyolysis: [14] [4] muscle pain, tenderness, or weakness; lack of energy; fever; chest pain; jaundice: yellowing of the skin or eyes; dark colored, or foamy urine; pain in the upper right ...
Statin-induced rhabdomyolysis is rare, occurring in less than 0.1% of people who take statins. [66] [67] [68] Statin induced rhabdomyolysis, as with other statin associated muscle symptoms, occurs most commonly in the first year of treatment but can occur at any time during treatment. [66]
The development of memory is a lifelong process that continues through adulthood. Development etymologically refers to a progressive unfolding. Memory development tends to focus on periods of infancy, toddlers, children, and adolescents, yet the developmental progression of memory in adults and older adults is also circumscribed under the umbrella of memory development.
Neuroplasticity is the process by which neurons adapt to a disturbance over time, and most often occurs in response to repeated exposure to stimuli. [27] Aerobic exercise increases the production of neurotrophic factors [note 1] (e.g., BDNF, IGF-1, VEGF) which mediate improvements in cognitive functions and various forms of memory by promoting blood vessel formation in the brain, adult ...
The statins differ with respect to their ring structure and substituents. These differences in structure affect the pharmacological properties of the statins, such as: [6] Affinity for the active site of the HMGR; Rates of entry into hepatic and non-hepatic tissues; Availability in the systemic circulation for uptake into non-hepatic tissues
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Cholesterol is the principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils. [3] [4]Cholesterol is biosynthesized by all animal cells [citation needed] and is an essential structural and signaling component of animal cell membranes.