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Torcetrapib (CP-529,414, Pfizer) was a drug being developed to treat hypercholesterolemia (elevated cholesterol levels) and prevent cardiovascular disease.Its development was halted in 2006 when phase III studies showed excessive all-cause mortality in the treatment group receiving a combination of atorvastatin (Lipitor) and torcetrapib.
Pfizer has been no stranger to the kind of damage that blockbuster drug patent expirations can inflict. The company's high-flying cholesterol fighter, Lipitor, has struggled since losing its ...
Pfizer introduced Lipitor in 1997, and the drug drove more than $130 billion in sales during its first 14 years on the market. The pharma distributors claimed Pfizer fraudulently sought to extend ...
Three U.S. senators are raising questions with Pfizer (NYS: PFE) over its deal making for its megablockbuster cholesterol drug Lipitor as generic drug makers step up to market the drug, most ...
From 1996 to 2012, under the trade name Lipitor, atorvastatin became the world's best-selling medication of all time, with more than $125 billion in sales over approximately 14.5 years. [ 118 ] and $13 billion a year at its peak, [ 119 ] Lipitor alone "provided up to a quarter of Pfizer Inc.'s annual revenue for years."
Cerivastatin (INN, [1] brand names: Baycol, Lipobay) is a synthetic member of the class of statins used to lower cholesterol and prevent cardiovascular disease.It was marketed by the pharmaceutical company Bayer A.G. in the late 1990s, competing with Pfizer's highly successful atorvastatin (Lipitor).