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Dermatomyositis is considered a type of inflammatory myopathy. [1] Diagnosis is typically based on some combination of symptoms, blood tests, electromyography , and muscle biopsies . [ 2 ] Eighty percent of adults [ 5 ] and sixty percent of children with juvenile dermatomyositis have a myositis-specific antibody (MSA).
Gottron's sign is a pathognomonic cutaneous manifestation associated with dermatomyositis (DM), which is an inflammatory disorder affecting the skin and muscles. [1] The primary lesion of dermatomyositis appears as a violaceous, macular erythema with a symmetric distribution, which may progress and become poikilodermatous (atrophic with telangiectasia and pigmentary changes) and indurated (as ...
It can also be associated with underlying cancer. The main classes of idiopathic inflammatory myopathy are polymyositis (PM), dermatomyositis (DM) (including juvenile, amyopathic, and sine-dermatitis form), inclusion-body myositis (IBM), immune-mediated necrotising myopathy (IMNM), and focal autoimmune myositis. [1]
dermatomyositis: Pathologic Basis of Disease (8th Ed), Robbins & Cotran: Scaling, erythematous eruption or dusky red patches over the knuckles, elbows and knees Gowers' sign [3] William Richard Gowers: neurology: muscular dystrophy: Graham Steell murmur: Graham Steell: cardiology: mitral stenosis
The three main types of idiopathic myositis (known as inflammatory myopathies) that typically test positive for autoantibodies are dermatomyositis, polymyositis, and inclusion body myositis. [4] Other autoimmune diseases, such as systemic lupus erythematosus , can also cause myositis-like symptoms.
Juvenile dermatomyositis (JDM) is an idiopathic inflammatory myopathy (IMM) of presumed autoimmune dysfunction resulting in muscle weakness among other complications. It manifests itself in children; it is the pediatric counterpart of dermatomyositis .
Gowers's sign is a medical sign that indicates weakness of the proximal muscles, namely those of the lower limb. The sign describes a patient that has to use their hands and arms to "walk" up their own body from a squatting position due to lack of hip and thigh muscle strength. It is named after William Richard Gowers. [1] [2]
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