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  2. Neurosteroid - Wikipedia

    en.wikipedia.org/wiki/Neurosteroid

    These neurosteroids have excitatory effects on neurotransmission. They act as potent negative allosteric modulators of the GABA A receptor, weak positive allosteric modulators of the NMDA receptor, and/or agonists of the σ 1 receptor, and mostly have antidepressant, anxiogenic, cognitive and memory-enhancing, convulsant, neuroprotective, and neurogenic effects.

  3. List of neurosteroids - Wikipedia

    en.wikipedia.org/wiki/List_of_neurosteroids

    Allopregnanolone, a major endogenous inhibitory neurosteroid. Steroid ring system.. This is a list of neurosteroids, or natural and synthetic steroids that are active on the mammalian nervous system through receptors other than steroid hormone receptors.

  4. Neurosteroidogenesis inhibitor - Wikipedia

    en.wikipedia.org/wiki/Neurosteroidogenesis_inhibitor

    A neurosteroidogenesis inhibitor is a drug that inhibits the production of endogenous neurosteroids.Neurosteroids include the excitatory neurosteroids pregnenolone sulfate, dehydroepiandrosterone (DHEA), and dehydroepiandrosterone sulfate (DHEA-S), and the inhibitory neurosteroids allopregnanolone, tetrahydrodeoxycorticosterone (THDOC), and 3α-androstanediol, among others. [1]

  5. Breakthrough antidepressants with fewer side effects could ...

    www.aol.com/finance/breakthrough-antidepressants...

    Ketamine’s antidepressant effects are part of what prompted researchers to explore other drugs that target glutamate—like the venerable cough suppressant dextromethorphan found in Robitussin ...

  6. List of investigational antidepressants - Wikipedia

    en.wikipedia.org/wiki/List_of_investigational...

    This is a list of investigational antidepressants, or drugs that are currently under development for clinical use in the treatment of depression but are not yet approved. Specific indications include major depressive disorder , treatment-resistant depression , dysthymia , bipolar depression , and postpartum depression , among others.

  7. Zuranolone - Wikipedia

    en.wikipedia.org/wiki/Zuranolone

    Zuranolone, sold under the brand name Zurzuvae, is a medication used for the treatment of postpartum depression. [5] [6] It is taken by mouth.[5]The most common side effects include drowsiness, dizziness, diarrhea, fatigue, nasopharyngitis, and urinary tract infection.

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