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Ancylostoma caninum is a species of nematode known as a hookworm, which principally infects the small intestine of dogs. [1] [2] [3] The result of A. caninum infection ranges from asymptomatic cases to death of the dog; better nourishment, increasing age, prior A. caninum exposure, or vaccination are all linked to improved survival.
In humans, treatment is by anthelminthic medications, such as albendazole and mebendazole. [13] Treatment in animals can be done with a variety of anthelminthics. [1] A high-protein diet, supplemental iron, or a blood transfusion may also be necessary. [1] Levamisole and pyrantel pamoate are also used to treat hookworm anemia and hookworm disease.
Hookworms infected about 428 million people in 2015. [4] Heavy infections can occur in both children and adults, but are less common in adults. [2] They are rarely fatal. [6] Hookworm infection is a soil-transmitted helminthiasis and classified as a neglected tropical disease. [7]
According to Lawrence, hookworms and whipworms -- parasitic worms, or helminths, that take up residence in the intestine -- induce a subdued inflammatory response more effectively than modern ...
A number of such organisms are currently being investigated for their use as treatment, including: Trichuris suis ova, [6] [7] commonly known as pig whipworm eggs; Necator americanus, [8] commonly known as hookworms; Trichuris trichiura ova, [9] commonly referred to as human whipworm eggs; and Hymenolepis diminuta, commonly known as rat tapeworm.
Mebendazole is a highly effective, broad-spectrum antihelmintic indicated for the treatment of nematode infestations, including roundworm, hookworm, whipworm, threadworm (pinworm), and the intestinal form of trichinosis prior to its spread into the tissues beyond the digestive tract.
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