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Pneumococcal polysaccharide vaccine, sold under the brand name Pneumovax 23, is a pneumococcal vaccine that is used for the prevention of pneumococcal disease caused by the 23 serotypes of Streptococcus pneumoniae contained in the vaccine as capsular polysaccharides. [2] It is given by intramuscular or subcutaneous injection. [2]
Children under the age of two years fail to mount an adequate response to the 23-valent adult vaccine, and so a pneumococcal conjugate vaccine is used. While this covers only seven strains out of more than ninety strains, these seven strains cause 80% to 90% of cases of severe pneumococcal disease, and it is considered to be nearly 100% ...
[49] [50] Additional pneumococcal vaccine research is taking place to find a vaccine that offers broad protection against pneumococcal disease. [51] As of 2017, pneumonia vaccines target up to 23 forms of the bacterium that cause pneumonia with a new version under development covering 72 strains of the bacterium. [52] [needs update]
There are around 100 different strains of the bacteria that can cause those infections. ... Merck's pneumococcal vaccine for adults ... to six weeks or older individuals and Pneumovax 23 for ...
Vaxneuvance covers 5 fewer serotypes, but the combination of Pneumovax 23 with Vaxneuvance covers more serotypes than Prevnar20. [15] Vaccines are heading for stronger protection against known serotypes, but also attack other strains or serotypes. [6]
Resistant pneumococcal strains are called penicillin-resistant pneumococci (PRP), [51] penicillin-resistant Streptococcus pneumoniae (PRSP), [52] Streptococcus pneumoniae penicillin resistant (SPPR) [53] or drug-resistant Strepotococcus pneumoniae (DRSP). In 2015, in the US, there were an estimated 30,000 cases, and in 30% of them the strains ...
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