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Fuchs dystrophy, also referred to as Fuchs endothelial corneal dystrophy (FECD) and Fuchs endothelial dystrophy (FED), is a slowly progressing corneal dystrophy that usually affects both eyes and is slightly more common in women than in men. Although early signs of Fuchs dystrophy are sometimes seen in people in their 30s and 40s, the disease ...
Toxic and nutritional optic neuropathy is a group of medical disorders defined by visual impairment due to optic nerve damage secondary to a toxic substance and/or nutritional deficiency. The causes of these disorders are various, but they are linked by shared signs and symptoms.
Posterior corneal dystrophies – Fuchs corneal dystrophy presents during the fifth or sixth decade of life. The characteristic clinical findings are excrescences on a thickened Descemet membrane (cornea guttae), generalized corneal edema and decreased visual acuity.
Copper disposition on corneal Descemet's membrane. Significant damage to the membrane may require a corneal transplant. Damage caused by the hereditary condition known as Fuchs dystrophy (q.v.)—where Descemet's membrane progressively fails and the cornea thickens and clouds because the exchange of nutrients/fluids between the cornea and the rest of the eye is interrupted—can be reversed by ...
The optic nerve contains axons of nerve cells that emerge from the retina, leave the eye at the optic disc, and go to the visual cortex where input from the eye is processed into vision. There are 1.2 million optic nerve fibers that derive from the retinal ganglion cells of the inner retina. [2] Damage to the optic nerve can have different causes:
Most cases of recurrent corneal erosion are acquired. There is often a history of recent corneal injury, such as corneal abrasion or ulcer, but also may be idiopathic or due to corneal dystrophy or corneal disease. In other words, one may develop corneal erosions as a result of another disorder, such as epithelial basement membrane dystrophy ...
superficial vein is percussed proximally; if impulse is felt over vein distally, valvular incompetence is present Budin's sign: Pierre-Constant Budin: surgery, obstetrics: suppurative mastitis: if breast milk flown into a sterile pad is mixed with pus (brown, yellow or bloody traces), mastitis may be present Brodie–Trendelenburg test
Alcohol dehydrogenase immunoreactivity in a healthy cornea (top), in Fuchs' dystrophy and keratoconic cornea. Diaminobenzidine stains keratocytes in the cross-section of cornea. From Mootha et al., 2009. [14] Keratocytes may play a role in different corneal disorders.