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Prurigo nodularis (PN), also known as nodular prurigo, is a skin disorder characterized by pruritic , nodular lesions, which commonly appear on the trunk, arms and legs. [1] Patients often present with multiple excoriated nodules caused by chronic scratching.
The cause of Acral persistent papular mucinosis is unknown, but genetic and environmental factors appear to play a role, as familial cases have been reported. [4] TNF-α and TGF-β have been proposed to stimulate glycosaminoglycan synthesis, however, the exact triggers are unknown.
There is no standard treatment for pityriasis lichenoides chronica. Treatments may include ultraviolet phototherapy, sun exposure, oral antibiotics, and corticosteroid creams and ointments to treat rash and itching. [3] [5] One study identified the enzyme bromelain as an effective therapeutic option for pityriasis lichenoides chronica. [6]
Histopathological image of dyshidrotic dermatitis, showing focal spongiotic change in the epidermis. Spongiosis is mainly intercellular [1] edema (abnormal accumulation of fluid) in the epidermis, [2] and is characteristic of eczematous dermatitis, manifested clinically by intraepidermal vesicles (fluid-containing spaces), "juicy" papules, and/or lichenification. [3]
Exam: The provider will look at your scalp, paying careful attention to signs of infection, redness, and bumps. Skin Swab: A swab of the affected area may be taken to be looked at more closely ...
Treatment with the 0.015% gel was found to completely clear 57% of AK, while the 0.05% gel had a 34% clearance rate. [62] Advantages of ingenol mebutate treatment include the short duration of therapy and a low recurrence rate. [63] Local skin reactions including pain, itching and redness can be expected during treatment with ingenol mebutate.
There is no confirmed treatment that directly interferes with the disease process. [5] [6] Cosmetic surgery to remove excessive skin has been used to improve aesthetic appearance in PXE patients [5] but because of the non-life-threatening nature of these symptoms, should be used with caution. [6]
Dyshidrosis is a type of dermatitis, characterized by itchy vesicles of 1–2 mm in size, on the palms of the hands, sides of fingers, or bottoms of the feet. [8] Outbreaks usually conclude within three to four weeks, but often recur.