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NIOSH, in response to the need for a working model as to what a "closed system" and what a "closed system drug transfer device" was, provided the following definition: "A drug transfer device that mechanically prohibits the transfer of environmental contaminants into the system and the escape of the hazardous drug or vapor concentrations ...
These phases are drug preparation, administration and disposal. Some studies have shown that while compounding hazardous drugs in a Class II BSC in conjunction with a closed-system drug transfer device, a significant decrease in drug contaminants inside a Class II BSC has resulted. [2]
USP 800 (Hazardous Drugs—Handling in Healthcare Settings) is a guideline created by the United States Pharmacopeia Convention (USP), as one of their General Chapters through which the USP "sets quality standards for medicines, dietary supplements and food ingredients".
Unlike its counterpart, the Occupational Safety and Health Administration, NIOSH's authority under the Occupational Safety and Health Act [29 CFR § 671] is to "develop recommendations for health and safety standards", to "develop information on safe levels of exposure to toxic materials and harmful physical agents and substances", and to "conduct research on new safety and health problems".
Drug disposal is the discarding of drugs. Individuals commonly dispose of unused drugs that remain after the end of medical treatment. [ 1 ] Health care organizations dispose of drugs on a larger scale for a range of reasons, including having leftover drugs after treating patients and discarding of expired drugs.
Hazardous Waste Operations and Emergency Response (HAZWOPER; / ˈ h æ z w ɒ p ər / HAZ-waw-pər) is a set of guidelines produced and maintained by the Occupational Safety and Health Administration which regulates hazardous waste operations and emergency services in the United States and its territories. [1]
The Occupational Safety and Health Act gives NIOSH the authority to conduct HHEs in the private sector and federal workplaces. When the workplace is part of a state or local government, NIOSH authority is more limited and the employer's cooperation may be necessary before NIOSH can do an evaluation. [3]
Exposure monitoring analyzes hazardous substances in the air or on surfaces of a workplace, and is complementary to biomonitoring, which instead analyzes toxicants or their effects within workers. A wide array of methods and instrumentation are used in workplace exposure monitoring.