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Vitiligo (/ ˌ v ɪ t ɪ ˈ l aɪ ɡ oʊ /, vi-ti-leye-goh) is a chronic autoimmune disorder that causes patches of skin to lose pigment or color. [1] The cause of vitiligo is unknown, but it may be related to immune system changes, genetic factors, stress, or sun exposure.
He diagnosed Jackson with lupus that year, [12] and with vitiligo in 1986. [13] Vitiligo's drastic effects on the body can cause psychological distress. Jackson used fair-colored makeup, [3] and possibly skin-bleaching prescription creams, [4] to cover up the uneven blotches of color caused by the illness.
The pigment loss can be partial (injury to the skin) or complete (caused by vitiligo). It can be temporary (from tinea versicolor) or permanent (from albinism). [1] Most commonly, depigmentation of the skin is linked to people born with vitiligo, which produces differing areas of light and dark skin. Monobenzone also causes skin depigmentation.
Severe atopic dermatitis has been linked to depigmentation resembling vitiligo. [3] With a prevalence of up to 59%, lichen striatus is another frequent cause of postinflammatory hypopigmentation. [4] Within two years, the dermatosis spontaneously heals, leaving temporary hypopigmentation, particularly in those with darker skin tones.
There are a wide range of depigmenting treatments used for hyperpigmentation conditions, and responses to most are variable. [11]Most often treatment of hyperpigmentation caused by melanin overproduction (such as melasma, acne scarring, liver spots) includes the use of topical depigmenting agents, which vary in their efficacy and safety, as well as in prescription rules.
Vitiligo: Topical steroids, including calcineurin inhibitors. Patients can also have transplants if they are stable or a depigmentation with topical MBEH if the patient has widespread discoloration. Chemical or drug induced leukoderma: Avoidance of causative agent with subsequent treatment similar to vitiligo. Piebaldism: None; occasionally ...