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Adrenocortical carcinoma (ACC) is an aggressive cancer originating in the cortex (steroid hormone-producing tissue) of the adrenal gland. Adrenocortical carcinoma is remarkable for the many hormonal syndromes that can occur in patients with steroid hormone-producing ("functional") tumors, including Cushing's syndrome , Conn syndrome ...
An adrenal tumor or adrenal mass [2] is any benign or malignant neoplasms of the adrenal gland, several of which are notable for their tendency to overproduce endocrine hormones. Adrenal cancer is the presence of malignant adrenal tumors, and includes neuroblastoma , adrenocortical carcinoma and some adrenal pheochromocytomas .
An adrenocortical adenoma or adrenal adenoma is commonly described as a benign neoplasm emerging from the cells that comprise the adrenal cortex. Like most adenomas , the adrenocortical adenoma is considered a benign tumor since the majority of them are non-functioning and asymptomatic .
Adenoid cystic carcinoma is a rare type of cancer that can exist in many different body sites. This tumor most often occurs in the salivary glands , but it can also be found in many anatomic sites, including the breast , [ 1 ] [ 2 ] lacrimal gland , lung , brain , Bartholin gland , trachea , and the paranasal sinuses .
Adrenocortical carcinoma, (ACC), is cancer that develops in the adrenal glands' cortex, or outer layer. [5] Adrenocortical carcinoma usually occurs randomly, independent of a genetic predisposition. [6] The majority of patients' primary complaints at first are indications and manifestations of excess hormones. [7]
Multiple Endocrine Neoplasia type 1 (MEN1) is a rare hereditary endocrine cancer syndrome characterized primarily by tumors of the parathyroid glands (95% of cases), endocrine gastroenteropancreatic (GEP) tract (30–80% of cases), and anterior pituitary (15–90% of cases). [19]
Adenomas of adrenal glands occurs occasionally in MEN 1 patients. Hormone secretion is rarely altered as a result, and the significance of these abnormalities is uncertain. Carcinoid tumors, particularly those derived from the embryologic foregut (lungs, thymus), occur in isolated cases.
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