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Letrozole, sold under the brand name Femara among others, is an aromatase inhibitor medication that is used in the treatment of breast cancer for post-menopausal women. [ 1 ] It was patented in 1986 and approved for medical use in 1996. [ 4 ]
Studies have shown that letrozole does not have adverse anti-estrogen-like effects on endometrial thickness and cervical mucus which seems to be explained by a short half-life. [5] Letrozole seems to be just as effective as clomiphene citrate for ovulation and pregnancy rate as it has shown to be very effective both in terms of ovulation rate ...
Lipoic acid (LA), also known as α-lipoic acid, alpha-lipoic acid (ALA) and thioctic acid, is an organosulfur compound derived from caprylic acid (octanoic acid). [3] ALA, which is made in animals normally, is essential for aerobic metabolism. It is also available as a dietary supplement or pharmaceutical drug in some countries.
There isn't a precise time of day to take blood pressure medication if you're trying to lower your heart attack risk. Traditionally, however, doctors have recommended people take blood pressure ...
Lipoic acid is an important co-factor in many enzyme systems, and one of them is the pyruvate dehydrogenase complex. [6] Studies that repressed the function of lipoyl synthase in Arabidopsis thaliana seeds showed that this did not have adverse effects on seed growth and weight, but shortened the generation time as well as the flowering time of ...
Central alpha agonists lower blood pressure by stimulating alpha-receptors in the brain which open peripheral arteries easing blood flow. These alpha 2 receptors are known as autoreceptors which provide negative feedback in neurotransmission (in this case, the vasoconstriction effects of adrenaline). Central alpha agonists, such as clonidine ...
Alpha lipoic acid (ALA) is an antioxidant that is made naturally by human cells. [50] It can also be administered in capsules or can be found in foods such as red meat, organ meats, and yeast. [50] Like other antioxidants, it functions by ridding the body of harmful free radicals that can cause damage to tissues and organs. [50]
One of the most common side effects with alpha blockers is the first dose effect. [29] This is a phenomenon in which patients with hypertension take an alpha blocker for the first time, and suddenly experience an intense decrease in blood pressure.