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  2. Signs and symptoms of HIV/AIDS - Wikipedia

    en.wikipedia.org/wiki/Signs_and_symptoms_of_HIV/AIDS

    The latency stage involves few or no symptoms and can last anywhere from two weeks to twenty years or more, depending on the individual. AIDS, the final stage of HIV infection, is defined by low CD4+ T cell counts (fewer than 200 per μL), various opportunistic infections, cancers, and other conditions.

  3. Pathophysiology of HIV/AIDS - Wikipedia

    en.wikipedia.org/wiki/Pathophysiology_of_HIV/AIDS

    The reason for the preferential loss of mucosal CD4 + T cells is that a majority of mucosal CD4 + T cells express the CCR5 coreceptor, whereas a small fraction of CD4 + T cells in the bloodstream do so. [5] HIV seeks out and destroys CCR5 expressing CD4 + cells during acute infection. A vigorous immune response eventually controls the infection ...

  4. HIV latency - Wikipedia

    en.wikipedia.org/wiki/HIV_latency

    Human Immunodeficiency Virus (HIV) has the capability to enter a latent stage of infection where it exists as a dormant provirus in CD4+ T-cells.Most latently infected cells are resting memory T cells, [1] however a small fraction of latently infected cells isolated from HIV patients are naive CD4 T cells.

  5. HIV/AIDS - Wikipedia

    en.wikipedia.org/wiki/HIV/AIDS

    HIV can also disseminate by direct transmission from one cell to another by a process of cell-to-cell spread. [96] [97] The hybrid spreading mechanisms of HIV contribute to the virus' ongoing replication against antiretroviral therapies. [95] [98] Two types of HIV have been characterized: HIV-1 and HIV-2. HIV-1 is the virus that was originally ...

  6. WHO Disease Staging System for HIV Infection and Disease in ...

    en.wikipedia.org/wiki/WHO_Disease_Staging_System...

    HIV encephalopathy ** And/or performance scale 4: bedridden > 50% of the day during last month. (*) HIV wasting syndrome: weight loss of > 10% of body weight, plus either unexplained chronic diarrhoea (> 1 month) or chronic weakness and unexplained prolonged fever (> 1 month).

  7. HIV set point - Wikipedia

    en.wikipedia.org/wiki/HIV_set_point

    The asymptomatic or clinical latency phase is marked by slow replication of the HIV virus, followed by steady depletion of CD4 T cells with little to no symptoms. For individuals that are rapid progressors, this phase can be short lived, with an average of 2-3 years. Long-term progressors (LTNPS) can remain stable in this stage for over a ...

  8. HIV - Wikipedia

    en.wikipedia.org/wiki/HIV

    Two types of HIV have been characterized: HIV-1 and HIV-2. HIV-1 is the virus that was initially discovered and termed both lymphadenopathy associated virus (LAV) and human T-lymphotropic virus 3 (HTLV-III). HIV-1 is more virulent and more infective than HIV-2, [20] and is the cause of the majority of HIV infections globally. The lower ...

  9. Misconceptions about HIV/AIDS - Wikipedia

    en.wikipedia.org/wiki/Misconceptions_about_HIV/AIDS

    Disease-specific drugs can also alleviate symptoms of AIDS and even cure specific AIDS-defining conditions in some cases. Medical treatment can reduce HIV infection in many cases to a survivable chronic condition. However, these advances do not constitute a cure, since current treatment regimens cannot eradicate latent HIV from the body.