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Enteric coating may also be used during studies as a research tool to determine drug absorption. [3] Enteric-coated medications pertain to the "delayed action" dosage form category. Tablets, mini-tablets, pellets and granules (usually filled into capsule shells) are the most common enteric-coated dosage forms. [3]
Coatings on a tablet or pellet may act as barriers to reducing the dissolution rate. Coatings may also be used to control where dissolution takes place. For example, enteric coatings only dissolve in the basic environment of the intestines. Drugs held in solution do not need to be dissolved before being absorbed.
Esomeprazole, sold under the brand name Nexium [or Neksium] among others, [2] is a medication which reduces stomach acid. [11] It is used to treat gastroesophageal reflux disease, peptic ulcer disease, and Zollinger–Ellison syndrome.
Enteric coated tablets are designed to dissolve in the intestine, not the stomach, because the drug present in the tablet causes irritation in the stomach. Administering medication rectally. The rectal route is an effective route of administration for many medications, especially those used at the end of life.
Tablets are easier to break accurately if scored, but there are devices called pill-splitters which cut unscored and scored tablets. Tablets with special coatings (for example, enteric coatings or controlled-release coatings) should not be broken before use, as this exposes the tablet core to the digestive juices, circumventing the intended ...
A film coating is a thin polymer-based coat that is typically sprayed onto solid pharmaceutical dosage forms, such as tablets, capsules, pellets or granules.Film coating can impact both its appearance and its pharmacokinetics making it an essential process in making the final drug product.