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  2. Fluoxetine - Wikipedia

    en.wikipedia.org/wiki/Fluoxetine

    Fluoxetine, sold under the brand name Prozac, among others, is an antidepressant medication of the selective serotonin reuptake inhibitor (SSRI) class [2] used for the treatment of major depressive disorder, anxiety, obsessive–compulsive disorder (OCD), panic disorder, premenstrual dysphoric disorder, and bulimia nervosa. [2]

  3. List of investigational antidepressants - Wikipedia

    en.wikipedia.org/wiki/List_of_investigational...

    This is a list of investigational antidepressants, or drugs that are currently under development for clinical use in the treatment of depression but are not yet approved. . Specific indications include major depressive disorder, treatment-resistant depression, dysthymia, bipolar depression, and postpartum depression, among oth

  4. Selective serotonin reuptake inhibitor - Wikipedia

    en.wikipedia.org/wiki/Selective_serotonin...

    The recommended maximum daily dose of citalopram and escitalopram was reduced due to concerns with QT prolongation. [92] [93] [94] In overdose, fluoxetine has been reported to cause sinus tachycardia, myocardial infarction, junctional rhythms, and trigeminy.

  5. Is It Time to Switch from Zoloft to Prozac? How to Tell

    www.aol.com/switching-zoloft-prozac-heres-expect...

    Switching from Zoloft to Prozac: What to Expect. Dealing with depression can feel overwhelming, whether you’re deep in a two-week funk or have been enduring it for years. And while depression is ...

  6. Antidepressant - Wikipedia

    en.wikipedia.org/wiki/Antidepressant

    [8] [9] [10] There is an increased risk of suicidal thinking and behavior when taken by children, adolescents, and young adults. [11] Discontinuation syndrome , which resembles recurrent depression in the case of the SSRI class, may occur after stopping the intake of any antidepressant, having effects which may be permanent and irreversible.

  7. Development and discovery of SSRI drugs - Wikipedia

    en.wikipedia.org/wiki/Development_and_discovery...

    Fluoxetine is a racemic mixture of (R)- and (S)-fluoxetine where both enantiomers contribute to its biological activity. [42] Since mono-substitution in the 4-para position of the phenoxy group ( figure 4 ) results in selective inhibition of 5-HT re-uptake, a disubstitution i.e. 2,3- or 2,4- substitution therefore results in a loss of SERT ...

  8. Breakthrough antidepressants with fewer side effects could ...

    www.aol.com/finance/breakthrough-antidepressants...

    The development of esketamine has helped shift attention beyond these neurotransmitters altogether. The FDA approved Johnson & Johnson’s drug for treatment-resistant depression in 2019.

  9. List of antidepressants - Wikipedia

    en.wikipedia.org/wiki/List_of_antidepressants

    This is a complete list of clinically approved prescription antidepressants throughout the world, as well as clinically approved prescription drugs used to augment antidepressants or mood stabilizers, by pharmacological and/or structural classification.