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Fluoxetine, sold under the brand name Prozac, among others, is an antidepressant medication of the selective serotonin reuptake inhibitor (SSRI) class [2] used for the treatment of major depressive disorder, anxiety, obsessive–compulsive disorder (OCD), panic disorder, premenstrual dysphoric disorder, and bulimia nervosa. [2]
This is a list of investigational antidepressants, or drugs that are currently under development for clinical use in the treatment of depression but are not yet approved. . Specific indications include major depressive disorder, treatment-resistant depression, dysthymia, bipolar depression, and postpartum depression, among oth
The recommended maximum daily dose of citalopram and escitalopram was reduced due to concerns with QT prolongation. [92] [93] [94] In overdose, fluoxetine has been reported to cause sinus tachycardia, myocardial infarction, junctional rhythms, and trigeminy.
Switching from Zoloft to Prozac: What to Expect. Dealing with depression can feel overwhelming, whether you’re deep in a two-week funk or have been enduring it for years. And while depression is ...
[8] [9] [10] There is an increased risk of suicidal thinking and behavior when taken by children, adolescents, and young adults. [11] Discontinuation syndrome , which resembles recurrent depression in the case of the SSRI class, may occur after stopping the intake of any antidepressant, having effects which may be permanent and irreversible.
Fluoxetine is a racemic mixture of (R)- and (S)-fluoxetine where both enantiomers contribute to its biological activity. [42] Since mono-substitution in the 4-para position of the phenoxy group ( figure 4 ) results in selective inhibition of 5-HT re-uptake, a disubstitution i.e. 2,3- or 2,4- substitution therefore results in a loss of SERT ...
The development of esketamine has helped shift attention beyond these neurotransmitters altogether. The FDA approved Johnson & Johnson’s drug for treatment-resistant depression in 2019.
This is a complete list of clinically approved prescription antidepressants throughout the world, as well as clinically approved prescription drugs used to augment antidepressants or mood stabilizers, by pharmacological and/or structural classification.