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Starbuck II, a clone of Holstein breeding bull Hanoverhill Starbuck, was born by Caesarean section on 7 September 2000. It was one of the first animals cloned for commercial purposes. [17] [18] In 2000, Texas A&M University cloned a Black Angus bull named 86 Squared, after cells from his donor, Bull 86, had been frozen for 15 years. Both bulls ...
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[110] [111] The best current cloning techniques have an average success rate of 9.4 percent [112] (and as high as 25 percent [37]) when working with familiar species such as mice, [note 1] while cloning wild animals is usually less than 1 percent successful. [115]
The only extinct animal to be cloned as of 2022 is a Pyrenean ibex, born on July 30, 2003, in Spain, which died minutes later due to physical defects in the lungs. [12] [13] Some animals have been cloned to add genetic diversity to endangered species with small remaining populations, thereby avoiding inbreeding depression.
Zhong Zhong (Chinese: 中中; pinyin: Zhōng Zhōng, born 27 November 2017) and Hua Hua (Chinese: 华华; pinyin: Huá Huá, born 5 December 2017) are a pair of identical crab-eating macaques (also referred to as cynomolgus monkeys) that were created through somatic cell nuclear transfer (SCNT), the same cloning technique that produced Dolly the sheep in 1996.
Dolly was the first clone produced from a cell taken from an adult mammal. [12] [13] The production of Dolly showed that genes in the nucleus of such a mature differentiated somatic cell are still capable of reverting to an embryonic totipotent state, creating a cell that can then go on to develop into any part of an animal. [2]
Polly and Molly (born 1997), two ewes, were the first mammals to have been successfully cloned from an adult somatic cell and to be transgenic animals at the same time. [1] This is not to be confused with Dolly the Sheep, the first animal to be successfully cloned from an adult somatic cell where there wasn’t modification carried out on the adult donor nucleus.