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The person has very few if any symptoms of sickle cell disease but carries the gene and can pass it on to their children. [56] Autosomal recessive inheritance means acquiring two changed genes from each parent. If both parents are carriers for the autosomal recessive gene, there is a 25% chance of their child having and expressing the disorder.
cTAKES ("clinical Text Analysis Knowledge Extraction Software") is a natural language processing system for extracting information from electronic medical record clinical free-text, an Apache top level project (TLP) since 2013, developed by the Mayo Clinic and others. It is available under the Apache license. [55]
The acute chest syndrome is a vaso-occlusive crisis of the pulmonary vasculature commonly seen in people with sickle cell anemia. This condition commonly manifests with a new opacification of the lung(s) on a chest x-ray .
[1] [2] Patients observe these symptoms and seek medical advice from healthcare professionals. Because most people are not diagnostically trained or knowledgeable, they typically describe their symptoms in layman's terms, rather than using specific medical terminology. This list is not exhaustive.
A vaso-occlusive crisis is a common painful complication of sickle cell anemia in adolescents and adults. [1] [2] It is a form of sickle cell crisis.Sickle cell anemia – most common in those of African, Hispanic, and Mediterranean origin – leads to sickle cell crisis when the circulation of blood vessels is obstructed by sickled red blood cells, causing ischemic injuries.
The sickle cell trait provides a survival advantage against malaria fatality over people with normal hemoglobin in regions where malaria is endemic. The trait is known to cause significantly fewer deaths due to malaria, especially when Plasmodium falciparum is the causative organism.
“The clinician’s primary job is to determine why symptoms of inattention are concerning and whether they are best attributed to ADHD, anxiety, depression, sleep, stress, changes in context ...
Sick cell syndrome is a medical condition characterised by reduced functioning of the cellular Na+/K+ pump, [1] which is responsible for maintaining the internal ion homeostasis.
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