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Blood group B has its highest frequency in the Middle East, where it ranks as the largest share of the population. In Southeast Asia its share of the population is lowest, especially in Indonesia, secondarily in East Asia , Northern Asia and neighboring Central Asia , and its incidence diminishes both towards the east and the west , falling to ...
A complete blood type would describe each of the 45 blood groups, and an individual's blood type is one of many possible combinations of blood-group antigens. [3] Almost always, an individual has the same blood group for life, but very rarely an individual's blood type changes through addition or suppression of an antigen in infection, malignancy, or autoimmune disease.
He defined that group A blood agglutinates with group B, but never with its own type. Similarly, group B blood agglutinates with group A. Group C blood is different in that it agglutinates with both A and B. [9] This was the discovery of blood groups for which Landsteiner was awarded the Nobel Prize in Physiology or Medicine in 1930.
The "O" blood type (usually resulting from the absence of both A and B alleles) is very common around the world, with a rate of 63% in all human populations. [135] Type "O" is the primary blood type among the Indigenous populations of the Americas, particularly within Central and South American populations, with a frequency of nearly 100%. [135]
The antigens Aua and Aub, known as the Auberger antigens, were once thought to make up a separate blood group but were later shown to be Lutheran antigens arising from variations in the BCAM gene. The phenotypes Lu(a+b−) and Lu(a+b+) are found at various frequencies within populations. The Lu(a−b+) phenotype is the most common in all ...
B cells, also known as B lymphocytes, are a type of white blood cell of the lymphocyte subtype. [1] They function in the humoral immunity component of the adaptive immune system . [ 1 ] B cells produce antibody molecules which may be either secreted or inserted into the plasma membrane where they serve as a part of B-cell receptors . [ 2 ]
The Duffy antigen/chemokine receptor gene (gp-Fy; CD234) is located on the long arm of chromosome 1 (1.q22-1.q23) and was cloned in 1993. [6] The gene was first localised to chromosome 1 in 1968, and was the first blood system antigen to be localised.
The Rh blood group system is a human blood group system. It contains proteins on the surface of red blood cells. After the ABO blood group system, it is most likely to be involved in transfusion reactions. The Rh blood group system consisted of 49 defined blood group antigens [1] in 2005.