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The findings show a decrease in mortality among people 60 years of age and older — including people over the age of 85 — who took statins. The study is published in Annals of Internal Medicine .
Statins appear to be effective at preventing cardiovascular disease and death in older adults, according to new research. Most clinical trials evaluating statins have not included people 75 and ...
The small number of available trials do not support the use of statins as an adjunctive therapy or as a monotherapy in multiple sclerosis. [223] A modelling study in the UK funded by the NIHR found that people aged 70 and older who take statins live longer in good health than those who do not, regardless of whether they have cardiovascular disease.
However, statins reduce cardiovascular disease events and total mortality irrespective of the initial cholesterol concentration. This is a major piece of evidence that statins work in another way than the lowering of cholesterol (called pleiotropic effects). [35]
[5] [6] [7] The study's authors estimated that the number needed to treat with rosuvastatin to prevent one cardiovascular event was 95 over two years, extrapolated to 25 over five years. The trial was stopped early, after just 1.9 years median duration, by the study's Independent Data Monitoring Board, because the interim results met the study ...
According to researchers, standard statin therapy normally results in a 35-45% reduction in LDL cholesterol, while higher-intensity treatment lowers LDL cholesterol by 45% or more. Lifetime statin ...