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Spillover: Animal Infections and the Next Human Pandemic is 2012 non-fiction book by David Quammen.The book, written in narrative form, tells through the personal experiences of the author, who interviewed numerous pathologists and virologists globally to trace the evolution of some of the major pathogens that have affected the human species following a species leap (), a natural process by ...
Virus latency (or viral latency) is the ability of a pathogenic virus to lie dormant within a cell, denoted as the lysogenic part of the viral life cycle. [1] A latent viral infection is a type of persistent viral infection which is distinguished from a chronic viral infection. Latency is the phase in certain viruses' life cycles in which ...
The precise role of double-stranded (ds)RNA is still widely investigated as a central player in the Interferon System. Groups have found that positive-strand RNA viruses and dsRNA viruses produced significant amounts of dsRNA, but the precise methods mammalian cells leverage to distinguish between self vs. non-self dsRNA have yet to be uncovered.
Polio is an infection caused by a virus that mostly affects children under 5. Most people infected with polio don’t have any symptoms, but it can cause fever, headaches, vomiting and stiffness ...
When the virus replicates faster than the immune system can control, it can destroy cells and harm the body, and it can even incite an over-zealous immune reaction that can cause other damage.
When the virus enters a cell, the cellular immune response is to protect the cell. The cell does so by wrapping the viral DNA around histones and condensing it into chromatin, causing the virus to become dormant, or latent. If cells are unsuccessful and the chromatin is loosely bundled, the viral DNA is still accessible.
She also said that if non-immunocompromised people feel well by day 11 but still test positive on an antigen test, “it is exceedingly unlikely” they’re still infectious.
As of the end of 2014, the vials were placed in a secure freezer to await destruction. The protocol for destruction of variola major virus involves a member of the WHO being present at the destruction. Usually the observer watches via closed-circuit television outside the room where the variola virus is autoclaved to destroy it.