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  2. Prazosin - Wikipedia

    en.wikipedia.org/wiki/Prazosin

    Prazosin has been said to be the only selective α 1-adrenergic receptor antagonist which has been used in the treatment of insomnia to any significant degree. [14] It is used at doses of 1 to 12 mg for this purpose. [14] The combination of prazosin and the beta blocker timolol may produce greater sedative effects than either of them alone. [15]

  3. Alpha blocker - Wikipedia

    en.wikipedia.org/wiki/Alpha_blocker

    High doses of the α 1 blocker, prazosin, have been efficacious in treating patients with PTSD induced nightmares due to its ability to block the effects of norepinephrine. [27] Adverse effects of prazosin to treat PTSD nightmares include dizziness, first dose effect (a sudden loss of consciousness), weakness, nausea, and fatigue. [27]

  4. Alpha-1 blocker - Wikipedia

    en.wikipedia.org/wiki/Alpha-1_blocker

    The risk of first dose phenomenon may be reduced or eliminated by gradual-dose titration, since the adverse effects of Prazosin are dose-related. [7] This is also the case for Tamsulosin and it may be assumed that the others alpha-1 blockers work in a similar manner, since Tamsulosin is an alpha-1-a blocker and Prazosin is an alpha-1 blocker. [30]

  5. Can Certain Foods Cause Nightmares? - AOL

    www.aol.com/lifestyle/food-can-certain-foods...

    Still, there isn't a lot of evidence to pinpoint which foods can specifically cause nightmares, but scientists are pretty certain that eating before bedtime is not the best idea.

  6. Nightmare - Wikipedia

    en.wikipedia.org/wiki/Nightmare

    Prazosin (alpha-1 blocker) appears useful in decreasing the number of nightmares and the distress caused by them in people with PTSD. [28] [29] Risperidone (atypical antipsychotic) at a dosage of 2 mg per day, has been shown in a case report to lead to the remission of nightmares on the first night. [29]

  7. List of drugs known for off-label use - Wikipedia

    en.wikipedia.org/wiki/List_of_drugs_known_for...

    Prazosin (Minipress) for nightmares: prazosin is approved for the use of hypertension. A 2012 systematic review showed a small benefit for the treatment of PTSD-associated night terrors. Other non-FDA-approved uses for prazosin include the treatment of Raynaud's disease and poisoning due to scorpion venom.

  8. Drive-by shooter who hit mourners at wake jailed - AOL

    www.aol.com/drive-shooter-hit-mourners-wake...

    The young girl injured in the stampede had been diagnosed with post-traumatic stress disorder (PTSD) and suffered from nightmares and flashbacks, as well as ongoing shoulder and neck pain, the ...

  9. First-dose phenomenon - Wikipedia

    en.wikipedia.org/wiki/First-dose_phenomenon

    This postural hypotension usually happens shortly after the first dose is absorbed into the blood and can result in syncope (fainting). Syncope occurs in approximately 1% of patients given an initial dose of 2 mg prazosin or greater. This adverse effect is self-limiting and in most cases does not recur after the initial period of therapy or ...