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Common side effects include abdominal pain, nausea, headaches, and muscle pains. [6] Serious side effects may include rhabdomyolysis, liver problems, and diabetes. [6] Use during pregnancy may harm the baby. [6] Like all statins, rosuvastatin works by inhibiting HMG-CoA reductase, an enzyme found in the liver that plays a role in producing ...
The difference in selectivity is because lipophilic statins passively and non-selectively diffuse into both hepatocyte and non-heptatocyte, while the hydrophilic statins rely largely on active transport into hepatocyte to exert their effects. [5] [12] High hepatoselectivity is thought to translate into reduced risk of adverse effects. [7]
Ezetimibe/rosuvastatin, sold under the brand name Ridutrin among others, is a combination medication used to treat high cholesterol. [6] [7] In some countries it is sold as a kit or a pack containing two distinct pills.
Water is without question the healthiest beverage any of us can be drinking. On top of that, it’s literally essential to life, with over 60 percent of our body consisting of water at any given time.
JUPITER was a randomized double-blind placebo-controlled study investigating the use of rosuvastatin in the primary prevention of cardiovascular disease.The trial focused on patients with normal low-density lipoprotein (LDL) cholesterol levels but increased levels of high-sensitivity C-reactive protein (hs-CRP).
Water had been fluoridated in Israel in all major cities since 1981. This was stopped by the Minister of Health in 2014 [82] which was met with backlash. [83] The subsequent Minister of Health in 2016 ordered the reintroduction of fluoride to Israel's public drinking water. [84] Due to budgetary constraints, it has never taken effect. [85]
Adipsia, also known as hypodipsia, is a symptom of inappropriately decreased or absent feelings of thirst. [1] [2] It involves an increased osmolality or concentration of solute in the urine, which stimulates secretion of antidiuretic hormone (ADH) from the hypothalamus to the kidneys.
Discontinuation of hydration does not produce true thirst, although a sensation of dryness of the mouth often is reported as "thirst". The evidence that true thirst does not occur is extensive, [ citation needed ] along with evidence showing that the ill feeling is not relieved by giving fluids intravenously, but rather by wetting the tongue ...