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Leukoplakia is, therefore, the most common premalignant lesion that occurs in the mouth. [41] Leukoplakia is more common in middle-aged and elderly males. [30] The prevalence increases with increasing age. [2] In areas of the world where smokeless tobacco use is common, there is a higher prevalence. [2]
Weight loss, < 10% of body weight; Minor mucocutaneous manifestations (seborrheic dermatitis, prurigo, fungal nail infections, recurrent oral ulcerations, angular cheilitis) Herpes zoster within the last five years; Recurrent upper respiratory tract infections (i.e. bacterial sinusitis) And/or performance scale 2: symptomatic, normal activity.
Hairy leukoplakia is a white patch on the side of the tongue with a corrugated or hairy appearance. It is caused by Epstein-Barr virus (EBV) and occurs usually in persons who are immunocompromised , especially those with human immunodeficiency virus infection/ acquired immunodeficiency syndrome (HIV/AIDS).
A precancerous condition is a condition, tumor or lesion involving abnormal cells which are associated with an increased risk of developing into cancer. [1] [2] [3] Clinically, precancerous conditions encompass a variety of abnormal tissues with an increased risk of developing into cancer.
Erythroplakia is analogous to the term leukoplakia which describes white patches. Together, these are the 2 traditionally accepted types of premalignant lesion in the mouth, [9] [10] When a lesion contains both red and white areas, the term "speckled leukoplakia" or "eyrthroleukoplakia" is used.
The cause is unknown, [2] but it is thought to be caused by intracellular edema of the superficial epithelial cells coupled with retention of superficial parakeratin. . Although leukoedema is thought to be a developmental condition, it may be more common and more pronounced in smokers, and becomes less noticeable when smoking is
Epidemic KS occurs in people with AIDS and many parts of the body can be affected. [8] KS is diagnosed by tissue biopsy, while the extent of disease may be determined by medical imaging. [4] [6] [8] Treatment is based on the sub-type, whether the condition is localized or widespread, and the person's immune function. [6]
Smoking most commonly leads to diseases affecting the heart and lungs and will commonly affect areas such as hands or feet. First signs of smoking-related health issues often show up as numbness in the extremities, with smoking being a major risk factor for heart attacks, chronic obstructive pulmonary disease (COPD), emphysema, and cancer, particularly lung cancer, cancers of the larynx and ...