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Microcytosis or microcythemia [1] is a condition in which red blood cells are unusually small as measured by their mean corpuscular volume. [ 2 ] When associated with anemia , it is known as microcytic anemia .
An example of this would be when a receptor normally lies on the basal or lateral membrane of an epithelial cell, but needs to be trafficked to the apical side. This can only be done through transcytosis due to tight junctions, which prevent movement from one plasma membrane domain to another. This type of cytosis occurs commonly in epithelium ...
Microcytic anaemia; Microcytosis is the presence of red cells that are smaller than normal. Normal adult red cell has a diameter of 7.2 µm. Microcytes are common seen in with hypochromia in iron-deficiency anaemia, thalassaemia trait, congenital sideroblastic anaemia and sometimes in anaemia of chronic diseases.
A blood smear showing hypochromic (and microcytic) anemia.Note the increased central pallor of the red blood cells. Hypochromic anemia is a generic term for any type of anemia in which the red blood cells are paler than normal.
The mean corpuscular volume, or mean cell volume (MCV), is a measure of the average volume of a red blood corpuscle (or red blood cell). The measure is obtained by multiplying a volume of blood by the proportion of blood that is cellular (the hematocrit), and dividing that product by the number of erythrocytes (red blood cells) in that volume.
A combination hemoglobinopathy occurs when someone inherits two different abnormal hemoglobin genes. If these are different versions of the same gene, one having been inherited from each parent it is an example of compound heterozygosity. Both alpha- and beta- thalassemia can coexist with other hemoglobinopathies.
These endocytosed molecules are sorted into early endosomes within the cell, which serves to further sort these substances to the correct final destination (in the same way the Golgi does in the secretory pathway). From here, the early endosome starts a cascade of transport where the cargo is eventually hydrolyzed inside the lysosome for ...
Light micrograph of a moss's leaf cells at 400X magnification. The following outline is provided as an overview of and topical guide to cell biology: . Cell biology – A branch of biology that includes study of cells regarding their physiological properties, structure, and function; the organelles they contain; interactions with their environment; and their life cycle, division, and death.