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  2. Proton-pump inhibitor - Wikipedia

    en.wikipedia.org/wiki/Proton-pump_inhibitor

    Proton-pump inhibitors have largely superseded the H 2-receptor antagonists, a group of medications with similar effects but a different mode of action, and heavy use of antacids. [3] A potassium-competitive acid blocker (PCAB) revaprazan was marketed in Korea as an alternative to a PPI.

  3. Discovery and development of proton pump inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    A derivative of timoprazole, omeprazole, was discovered in 1979, and was the first of a new class of drug that control acid secretion in the stomach, a proton pump inhibitor (PPI). [11] [12] Addition of 5-methoxy-substitution to the benzimidazole moiety of omeprazole was also made and gave the compound much more stability at neutral pH. [6]

  4. Drugs for acid-related disorders - Wikipedia

    en.wikipedia.org/wiki/Drugs_for_acid-related...

    Proton-pump inhibitors are named using the suffix "-prazole". There is a purported correlation (but no proven causal link) between the use of PPIs and the risk of dementia. [ 6 ] However, this remain controversial as chronic and co-morbid pathology, and resultant polypharmacy (including increased consumption of PPIs), will probably itself also ...

  5. What Dietitians Want You to Know About Drinks for Acid Reflux

    www.aol.com/dietitians-want-know-drinks-acid...

    Antacids, H2 blockers (which work to reduce stomach acid), and proton pump inhibitors (PPIs) may provide relief from acid reflux symptoms. However, always consult a healthcare professional before ...

  6. Pantoprazole - Wikipedia

    en.wikipedia.org/wiki/Pantoprazole

    Pantoprazole is a proton pump inhibitor that decreases gastric acid secretion. [5] It works by inactivating (H+/K+)-ATPase function in the stomach. [9] [5] The study of pantoprazole began in 1985, and it came into medical use in Germany in 1994. [10] It is available as a generic medication.

  7. Anti-ulcer agents - Wikipedia

    en.wikipedia.org/wiki/Anti-ulcer_agents

    Several anti-ulcer dosing regimens that combine antibiotics and proton pump inhibitors (PPI) to treat helicobacter pylori (H. pylori) induced peptic ulcer disease (PUD). The role of antibiotic in the therapies is to eradicate H. pylori, while the action of PPI is to reduce gastric acid secretion. The anti-ulcer dosing regimens generally repair ...

  8. Rabeprazole - Wikipedia

    en.wikipedia.org/wiki/Rabeprazole

    Rabeprazole is available in 10 and 20 mg, delayed-release tablets (pictured below). [6] Rabeprazole-based products, like other proton pump inhibitor products, have to be formulated in delayed-release tablets to protect the active medication from being degraded by the acid of the stomach before being absorbed.

  9. Lansoprazole - Wikipedia

    en.wikipedia.org/wiki/Lansoprazole

    It is a proton pump inhibitor (PPI), used to treat peptic ulcer disease, gastroesophageal reflux disease, and Zollinger–Ellison syndrome. [5] Its effectiveness is similar to that of other PPIs. [6] It is taken by mouth. [4] Onset is over a few hours and effects last up to a couple of days. [4]