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Progestogens, also sometimes written progestins, progestagens or gestagens, [1] are a class of natural or synthetic steroid hormones that bind to and activate the progesterone receptors (PR). [ 2 ] [ 3 ] Progesterone is the major and most important progestogen in the body.
Progestogens are used most commonly in hormonal birth control and menopausal hormone therapy. [1] They can also be used in the treatment of gynecological conditions, to support fertility and pregnancy, to lower sex hormone levels for various purposes, and for other indications. [1] Progestogens are used alone or in combination with estrogens. [1]
Progesterone (/ p r oʊ ˈ dʒ ɛ s t ər oʊ n / ⓘ; P4) is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species.
[28] [20] The medication is a naturally occurring progestogen and hence is an agonist of the progesterone receptor (PR), the biological target of progestogens like endogenous progesterone. [20] It opposes the effects of estrogens in various parts of the body like the uterus and also blocks the effects of the hormone aldosterone.
Other contexts will include progestogens as a third class of sex steroids, distinct from androgens and estrogens. [5] Progesterone is the most important and only naturally occurring human progestogen. In general, androgens are considered "male sex hormones", since they have masculinizing effects, while estrogens and progestogens are considered ...
This is a list of progestogens that are or that have been used in clinical or veterinary medicine. They are steroids and include derivatives of progesterone and testosterone . Progesterone derivatives
Hormones during pregnancy are the result of an intricate interaction between hormones generated by different glands and organs.The primary hormones involved comprise human chorionic gonadotropin (hCG), progesterone, estrogen, human placental lactogen (hPL), and oxytocin.
Progestogens share the common feature of being able to bind to the body's progesterone receptors and enact a physiological effect similar to naturally occurring progesterone. [11] Still, there are differences between progestogens, and various organizational systems exist to categorize the progestogen hormones used in oral contraception medications.