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  2. Your Gout Guide: From Symptoms to Treatment - AOL

    www.aol.com/gout-guide-symptoms-treatment...

    If you have untreated gout for a long time, something called tophi can develop. Tophi is when uric acid crystals around the joints form larger, hard deposits. It can lead to pain, soft tissue ...

  3. Wikipedia:VideoWiki/Gout - Wikipedia

    en.wikipedia.org/wiki/Wikipedia:VideoWiki/Gout

    Steps for video creation; Step 1: ... Definition. Gout is a form of inflammatory arthritis characterized by ... It may also result in tophi, kidney stones ...

  4. Tophus - Wikipedia

    en.wikipedia.org/wiki/Tophus

    A tophus (Latin: "stone", pl.: tophi) is a deposit of monosodium urate crystals, in people with longstanding high levels of uric acid (urate) in the blood, a condition known as hyperuricemia. Tophi are pathognomonic for the disease gout. Most people with tophi have had previous attacks of acute arthritis, eventually leading to the formation of ...

  5. Gout - Wikipedia

    en.wikipedia.org/wiki/Gout

    Gout presenting as slight redness in the metatarsophalangeal joint of the big toe. Gout can present in several ways, although the most common is a recurrent attack of acute inflammatory arthritis (a red, tender, hot, swollen joint). [4] The metatarsophalangeal joint at the base of the big toe is affected most often, accounting for half of cases ...

  6. Wikipedia : VideoWiki/Gout/gallery

    en.wikipedia.org/wiki/Wikipedia:VideoWiki/Gout/...

    Gout is a form of inflammatory arthritis characterized by recurrent attacks of a single red, tender, hot, and swollen joint. [ 1 ] [ 2 ] Pain typically comes on rapidly, reaching maximal intensity in less than twelve hours. [ 3 ]

  7. Uricosuric - Wikipedia

    en.wikipedia.org/wiki/Uricosuric

    Uricosurics are often used in the treatment of gout, a disease in which uric acid crystals form deposits in the joints. By decreasing plasma uric acid levels, help dissolve these crystals, while limiting the formation of new ones. However, the increased uric acid levels in urine can contribute to kidney stones.

  8. Pegloticase - Wikipedia

    en.wikipedia.org/wiki/Pegloticase

    Pegloticase (trade name Krystexxa) is a medication for the treatment of severe, treatment-refractory, chronic gout. It is a third line treatment in those in whom other treatments are not effective or are not tolerated. [2] The drug is administered by infusion intravenously. Since October 2023, Amgen Inc. has been the marketer of pegloticase in ...

  9. Heberden's node - Wikipedia

    en.wikipedia.org/wiki/Heberden's_node

    Heberden's nodes are hard or bony swellings that can develop in the distal interphalangeal joints (DIP) (the joints closest to the end of the fingers and toes). [1] They are a sign of osteoarthritis and are caused by formation of osteophytes (calcific spurs) of the articular (joint) cartilage in response to repeated trauma at the joint.