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Pyotraumatic dermatitis is caused by self-inflicted trauma to the skin, which is incited by pain or irritation, such as infestation with fleas or lice, [4] irritation from clippers, [3] allergic skin diseases, [4] diseases of the anal sacs, [4] inflammation of the ear canal, [4] foreign bodies or irritants within the coat, [4] or pain in muscles or joints. [4]
Itching, pain, and weakness of the body have been observed in some cases. Other symptoms of Pemphigus foliaceus include hair loss, formation of pustules, and erosions with ulcers. These symptoms can appear on the dog's feet, groin area, and trunk if left untreated. [16]
The condition of a dog's skin and coat is also an important indicator of its general health. Skin disorders of dogs vary from acute, self-limiting problems to chronic or long-lasting problems requiring life-time treatment. Skin disorders may be primary or secondary (due to scratching, itch) in nature, making diagnosis complicated.
Dogs are susceptible to allergies much like their human companions. Most allergies occur in dogs over 6 months old. A dog that is repeatedly exposed to a particular allergen becomes sensitized to it, and the immune system overreacts to a subsequent exposure, most commonly manifesting in the form of skin irritation. [1]
A lick granuloma, also known as acral lick dermatitis, is a skin disorder found most commonly in dogs, but also in cats. In dogs, it results typically from the dog's urge to lick the lower portion of one of their legs. The lesion can initially be red, swollen, irritated, and bleeding, similar to a hot spot (wet eczema).
The formalin assay is the most popular chemical assay of nociception.It entails the injection of a dilute solution of formalin into the surface of the rodent's hindpaw, followed by the scoring of stereotypical behaviors such as flinching, licking, and biting of the affected hindpaw. [1]