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Lupus erythematosus is a collection of autoimmune diseases in which the human immune system becomes hyperactive and attacks healthy tissues. [1] Symptoms of these diseases can affect many different body systems, including joints , skin , kidneys , blood cells , heart , and lungs .
Clinical criteria: Individuals exhibiting 1) lesions that occur in acute cutaneous lupus erythematosus such as a malar rash, toxic epidermal necrolysis, bullae, (i.e., large blisters containing serous fluid), maculopapular rashes, photosensitive lupus-like rashes (in individuals who do not have dermatomyositis), or subacute cutaneous lupus ...
Subacute cutaneous lupus erythematosus (SCLE ) is a clinically distinct subset of cases of lupus erythematosus that is most often present in white women aged 15 to 40, consisting of skin lesions that are scaly and evolve as poly-cyclic annular lesions or plaques similar to those of plaque psoriasis. [1]
Lupus patches on the cheek, ear, and scalp Widespread lupus patches across the face with an epithelioma. As many as 70% of people with lupus have some skin symptoms. The three main categories of lesions are chronic cutaneous (discoid) lupus, subacute cutaneous lupus, and acute cutaneous lupus.
The presence of Anti-Ro/SSA antibodies also correlates with symptoms of photosensitivity, cutaneous vasculitis, and hematological disorders. [3] In individuals with cutaneous lupus erythematosus (CLE), a subcategory of lupus erythematosus, elevated levels of Ro52 are found regardless of expression of Anti-Ro autoantibodies.
Acute cutaneous lupus erythematosus; ... Subacute cutaneous lupus erythematosus ... Photosensitivity–ichthyosis–brittle sulfur-deficient hair–impaired ...
Lupus erythematosus tumidus (LET) was reported by Henri Gougerot and Burnier R. in 1930. It is a photosensitive skin disorder, a different subtype of cutaneous lupus erythematosus (CLE) from discoid lupus erythematosus (DLE) or subacute CLE (SCLE). [3] LET is usually found on sun-exposed areas of the body.
Lupus erythematosus panniculitis consists of soft, deep subcutaneous plaques or nodules that can occasionally appear in crops. Proximal extremities, in particular the lateral aspects of the arms and shoulders, face, trunk, buttocks breast, and scalp, are typically involved.