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An ultra-fast tool to find relative absent words in genomic data Nucleotide ACT (Artemis Comparison Tool) Synteny and comparative genomics Nucleotide AVID Pairwise global alignment with whole genomes: Nucleotide BLAT Alignment of cDNA sequences to a genome. Nucleotide DECIPHER: Alignment of rearranged genomes using 6 frame translation ...
In bioinformatics, BLAST (basic local alignment search tool) [3] is an algorithm and program for comparing primary biological sequence information, such as the amino-acid sequences of proteins or the nucleotides of DNA and/or RNA sequences.
The fourth is a great example of how interactive graphical tools enable a worker involved in sequence analysis to conveniently execute a variety if different computational tools to explore an alignment's phylogenetic implications; or, to predict the structure and functional properties of a specific sequence, e.g., comparative modelling.
The NCBI assigns a unique identifier (taxonomy ID number) to each species of organism. [5] The NCBI has software tools that are available through web browsers or by FTP. For example, BLAST is a sequence similarity searching program. BLAST can do sequence comparisons against the GenBank DNA database in less than 15 seconds.
SOAP (Short Oligonucleotide Analysis Package) is a suite of bioinformatics software tools from the BGI Bioinformatics department enabling the assembly, alignment, and analysis of next generation DNA sequencing data. It is particularly suited to short read sequencing data.
T-Coffee (Tree-based Consistency Objective Function for Alignment Evaluation) is a multiple sequence alignment software using a progressive approach. [1] It generates a library of pairwise alignments to guide the multiple sequence alignment.
MAFFT is widely considered to be one of the most accurate and versatile tools for multiple sequence alignment in bioinformatics. In fact, studies have shown that MAFFT performs exceptionally well when compared to other popular algorithms such as Clustal W and T-Coffee , particularly for larger datasets and sequences with high degrees of ...
Multiple sequence alignment: Clustal W and O, MUSCLE, Kalign, MAFFT, T-Coffee; Create and use shared storage, e.g., lab database; Search through online databases: National Center for Biotechnology Information (NCBI), Protein Data Bank (PDB), UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, DAS servers; Local and NCBI Genbank BLAST search; Open reading ...