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  2. Venereal Disease Research Laboratory test - Wikipedia

    en.wikipedia.org/wiki/Venereal_Disease_Research...

    The VDRL is a nontreponemal serological screening for syphilis that is also used to assess response to therapy, to detect central nervous system involvement, and as an aid in the diagnosis of congenital syphilis. The basis of the test is that an antibody produced by a patient with syphilis reacts with an extract of ox heart (diphosphatidyl ...

  3. Congenital syphilis - Wikipedia

    en.wikipedia.org/wiki/Congenital_syphilis

    Serological testing is more commonly carried out on the mother and the infant to diagnose maternal and congenital syphilis. In the mother, a serologic diagnosis of syphilis is made using a nontreponemal test for syphilis such as the Venereal Disease Research Laboratory test or Rapid plasma reagin (RPR) followed by a treponemal test, such as the ...

  4. Treponema pallidum particle agglutination assay - Wikipedia

    en.wikipedia.org/wiki/Treponema_pallidum...

    For primary syphilis, TPPA has a sensitivity of 85% to 100%, and a specificity of 98% to 100%. [2] In secondary and late-latent syphilis, TPPA has a sensitivity of 98% to 100%. [2] Antibodies against other treponemal organisms, such as the T. pallidum subspecies endemicum, pertenue, or carateum, can cause false positive results.

  5. Newborn syphilis cases have reached 'dire levels,' CDC says - AOL

    www.aol.com/news/newborn-syphilis-cases-reached...

    Testing someone for syphilis doesn't necessarily mean they'll get treated, though: Out of almost 2,200 congenital syphilis cases last year in which the infant's birth parent received timely ...

  6. Infant syphilis cases are skyrocketing in the US: ‘Shameful ...

    www.aol.com/infant-syphilis-cases-skyrocketing...

    CDC says that more than 3,700 cases of congenital syphilis were reported in 2022, around 11 times the number recorded a decade ago

  7. Syphilis - Wikipedia

    en.wikipedia.org/wiki/Syphilis

    Latent syphilis is defined as having serologic proof of infection without symptoms of disease. [19] It develops after secondary syphilis and is divided into early latent and late latent stages. [27] Early latent syphilis is defined by the World Health Organization as less than 2 years after original infection. [27]

  8. ‘Alarming’ rise of syphilis reported in KY newborns and ...

    www.aol.com/alarming-rise-syphilis-reported-ky...

    Syphilis spreads through sexual contact (vaginal, anal or oral sex) and from a pregnant mother to her unborn baby. After infection, the disease progresses gradually in four stages. Each exhibits ...

  9. Rapid plasma reagin - Wikipedia

    en.wikipedia.org/wiki/Rapid_plasma_reagin

    The rapid plasma reagin test (RPR test or RPR titer) is a type of rapid diagnostic test that looks for non-specific antibodies in the blood of the patient that may indicate an infection by syphilis or related non-venereal treponematoses. It is one of several nontreponemal tests for syphilis (along with the Wassermann test and the VDRL test).