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At steady state, the systemic exposure for armodafinil is 1.8 times the exposure observed after a single dose. The concentration-time profiles of the (R)-(−)-enantiomer following a single dose of 50 mg Nuvigil or 100 mg Provigil (modafinil being a 1:1 mixture of (R)-(−)- and (S)-(−)- enantiomers
Modafinil, sold under the brand name Provigil among others, is a central nervous system (CNS) stimulant and eugeroic (wakefulness promoter) medication used primarily to treat narcolepsy, [3] [8] [15] a sleep disorder characterized by excessive daytime sleepiness and sudden sleep attacks. [16]
Methamphetamine [note 1] (contracted from N-methylamphetamine) is a potent central nervous system (CNS) stimulant that is mainly used as a recreational or performance-enhancing drug and less commonly as a second-line treatment for attention deficit hyperactivity disorder (ADHD). [23]
Different ATS also have different toxic dose. Methamphetamine fatality from ATS have been reported after ingestion of a minimal dose of 1.3 mg/kg, while the estimated minimum lethal dose in a non-addicted adult is 200 mg. [14] [26] Generally, children are more likely to develop toxicity and have lower chances of developing tolerance. [14]
An analysis revealed Mares’ fingerprints on a bag containing 380 grams of methamphetamine found in the safe, according to federal prosecutors, who say a loaded firearm was also recovered from a ...
Officials later found 3,750 grams of drugs and precursor ... Officials estimated the street value of the drugs to be more than $2.2 million, making it the largest illicit pharmaceutical seizure in ...
Methamphetamine accounts for 84% of illegal drug use in Japan and has a relatively high street value in the country (around 10 times the street value in production regions). [18] Netherlands: Unenforced: Illegal: Illegal: Illegal: Methamphetamine is not approved for medical use in The Netherlands. It falls under Schedule I of the Opium Act. [19]
Richmond police said they received a report of shots fired just after 8 p.m. in the 1200 block of Harris Street. ... Richmond man arrested; 100 grams of meth and altered firearm seized. Show comments.