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5α-Reductase inhibitors (5-ARIs), also known as dihydrotestosterone (DHT) blockers, are a class of medications with antiandrogenic effects which are used primarily in the treatment of enlarged prostate and scalp hair loss. They are also sometimes used to treat excess hair growth in women and as a component of hormone therapy for transgender ...
This is a list of 5α-reductase inhibitors (5α-RIs), drugs which inhibit one or more isoforms of the enzyme 5α-reductase.This enzyme is responsible for the conversion of the androgen hormone testosterone into the more potent dihydrotestosterone (DHT) and is essential for the production of neurosteroids like allopregnanolone, tetrahydrodeoxycorticosterone (THDOC), and 3α-androstanediol from ...
Since DHT is the main cause of androgenetic or androgenic alopecia, a DHT blocker can be the best way to treat pattern baldness. Just keep in mind: Not all DHT blockers are equally effective.
5-alpha reductase blockers reduce DHT levels, slowing down, stopping, or reversing the effects of male pattern baldness. They can also encourage hair regrowth and increase hair count.
Saw palmetto is the champion DHT blocker, which helps prevent further hair loss or thinning. While saw palmetto helps fight hair follicle shrinkage, vegan biotin strengthens the hair, ensuring it ...
Dutasteride (Avodart) was the second steroidal 5α-reductase approved after finasteride. It is a competitive inhibitor of all three 5α-reductase isoenzymes [4] and it inhibits types 1 and 2 better than finasteride, leading to it causing further reduction in DHT, with >90% reduced DHT levels following 1 year of oral administration. [1]