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Certain medical procedures can also injure the airways; these include tracheal intubation, bronchoscopy, and tracheotomy. [4] The back of the trachea may be damaged during tracheotomy. [18] TBI resulting from tracheal intubation (insertion of a tube into the trachea) is rare, and the mechanism by which it occurs is unclear. [19]
Permanent brain damage can occur after as little as three minutes and death will inevitably ensue after a few more minutes unless ventilation is restored. However, under special circumstances such as hypothermia , hyperbaric oxygenation , apneic oxygenation (see below), or extracorporeal membrane oxygenation , much longer periods of apnea may ...
Bronchoscopy is an endoscopic technique of visualizing the inside of the airways for diagnostic and therapeutic purposes. An instrument ( bronchoscope ) is inserted into the airways, usually through the nose or mouth, or occasionally through a tracheostomy .
Damage to the brain (such as from a massive stroke, non-penetrating head injury, intoxication or poisoning) may result in a depressed level of consciousness. When this becomes severe to the point of stupor or coma (defined as a score on the Glasgow Coma Scale of less than 8), [ 3 ] dynamic collapse of the extrinsic muscles of the airway can ...
Neurogenic shock results from damage to the spinal cord above the level of the 6th thoracic vertebra. [5] It is found in about half of people who have a spinal cord injury within the first 24 hours, and usually persists for one to three weeks. [5] Neurogenic shock may be caused by severe brain injury. [6]
High levels of intracellular Ca 2+, the major cause of post-injury cell damage, [30] destroy mitochondria, [11] and trigger phospholipases and proteolytic enzymes that damage Na+ channels and degrade or alter the cytoskeleton and the axoplasm. [31] [26] Excess Ca 2+ can also lead to damage to the blood–brain barrier and swelling of the brain ...
The risk of death from an intraparenchymal bleed in traumatic brain injury is especially high when the injury occurs in the brain stem. [48] Intraparenchymal bleeds within the medulla oblongata are almost always fatal, because they cause damage to cranial nerve X, the vagus nerve, which plays an important role in blood circulation and breathing ...
Not everyone fully heals from brain damage, but it is possible to have a full recovery. Brain injuries are very hard to predict in outcome. Many tests and specialists are needed to determine the likelihood of the prognosis. People with minor brain damage can have debilitating side effects; not just severe brain damage has debilitating effects. [49]