Search results
Results From The WOW.Com Content Network
Hyposplenism is used to describe reduced ('hypo-') splenic functioning, but not as severely affected as with asplenism. Functional asplenia occurs when splenic tissue is present but does not work well (e.g. sickle-cell disease, polysplenia ) – such patients are managed as if asplenic – while in anatomic asplenia , the spleen itself is absent.
Howell–Jolly bodies are seen with markedly decreased splenic function. Common causes include asplenia (post-splenectomy) or congenital absence of spleen (right atrial appendage isomerism). Spleens are also removed for therapeutic purposes in conditions like hereditary spherocytosis , trauma to the spleen, and autosplenectomy caused by sickle ...
The spleen is an organ within the lymphatic system and its primary function is to filter blood. However, the spleen also plays a key role in immune responses as it detects pathogens within the blood and secretes phagocytes to fight potential infection. Without these immune functions, individuals with isolated congenital asplenia are extremely ...
The spleen is an important immunological organ that acts as a filter for red blood cells, triggers phagocytosis of invaders, and mounts an immunological response when necessary. [2] Lack of a spleen, called asplenia, can occur by autosplenectomy or the surgical counterpart, splenectomy. Asplenia can increase susceptibility to infection. [3]
The spleen is innervated by the splenic plexus, which connects a branch of the celiac ganglia to the vagus nerve. The underlying central nervous processes coordinating the spleen's function seem to be embedded into the hypothalamic-pituitary-adrenal-axis, and the brainstem, especially the subfornical organ. [17]
Polysplenia is a congenital disease manifested by multiple small accessory spleens, [1] rather than a single, full-sized, normal spleen.Polysplenia sometimes occurs alone, but it is often accompanied by other developmental abnormalities.
The spleen is an important organ in regard to immunological function due to its ability to efficiently destroy encapsulated bacteria. Therefore, removal of the spleen runs the risk of overwhelming post-splenectomy infection , a medical emergency and rapidly fatal disease caused by the inability of the body's immune system to properly fight ...
An image of the spleen in the human body. Also shows the red and white pulp regions. Splenocytes are spleen cells and consist of leukocytes like B and T cells, dendritic cells, and macrophages. [2] The spleen is split into red and white pulp regions with the marginal zone separating the two areas. The red pulp is involved with filtering blood ...