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Lichen planus may be categorized as affecting mucosal or cutaneous surfaces.. Cutaneous forms are those affecting the skin, scalp, and nails. [10] [11] [12]Mucosal forms are those affecting the lining of the gastrointestinal tract (mouth, pharynx, esophagus, stomach, anus), larynx, and other mucosal surfaces including the genitals, peritoneum, ears, nose, bladder and conjunctiva of the eyes.
Oral lichen planus (OLP) is a chronic inflammatory T- cellular disorder that strikes the oral mucosa. In a clinical report in 2022, [28] a fast resolving of OLP was achieved in a patient treated with Abrocitinib. A dose of 200 mg of Abrocitinib was administered daily as monotherapy for twelve weeks.
It has been proven to be effective in various inflammatory skin diseases, e.g., seborrheic dermatitis, [2] cutaneous lupus erythematosus, [3] oral lichen planus, [4] vitiligo, [5] and psoriasis. [6] [7] Tacrolimus and pimecrolimus are both calcineurin inhibitors and function as immunosuppressants. [8]
Lichen planus What it looks like : Purplish lesions on the inner arms, legs, wrists, or ankles can signify lichen planus, a skin rash triggered by an overreaction of the immune system.
Lichen planus is an inflammatory skin disease. When it affects the scalp, it’s called lichen planopilaris . There’s a lot we don’t know about lichen planus and lichen planopilaris, but they ...
Moderate steroids are used for atopic dermatitis, nummular eczema, xerotic eczema, lichen sclerosis et atrophicus of the vulva, scabies (after scabiecide) and severe dermatitis. Strong steroids are used for psoriasis , lichen planus , discoid lupus , chapped feet, lichen simplex chronicus , severe poison ivy exposure, alopecia areata , nummular ...
Clobetasol propionate is used for the treatment of various skin disorders including eczema, herpes labialis, [16] psoriasis, and lichen sclerosus.It is also used to treat several auto-immune diseases including alopecia areata, lichen planus (auto immune skin nodules), and mycosis fungoides (T-cell skin lymphoma).
It has mild immunosuppressive effects [1] and may displace thyroid hormone from its binding protein. [2] [3] It can also cause lichen planus. [4] Due to its side effects it was withdrawn from the UK and US in the 1980s.