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Lichen planus may be categorized as affecting mucosal or cutaneous surfaces.. Cutaneous forms are those affecting the skin, scalp, and nails. [10] [11] [12]Mucosal forms are those affecting the lining of the gastrointestinal tract (mouth, pharynx, esophagus, stomach, anus), larynx, and other mucosal surfaces including the genitals, peritoneum, ears, nose, bladder and conjunctiva of the eyes.
Although the precise cause of the condition is unknown, as it is thought to be a variation of lichen planus, cell-mediated immunity—a type of immune system—may be a crucial factor in the development of the disease's clinical manifestation. [3]
It can be a manifestation of lichen planus, psoriasis, alopecia areata, immunoglobulin A deficiency, atopic dermatitis, and ichthyosis vulgaris. [7] "The longitudinal striations can occur as a normal part of the aging process", [2] and not until the nails start to thin and get a sandpaper look is the condition called trachonychia. The nails are ...
Dr. Michael Chancellor, Lipella’s Chief Medical Officer and author of the paper, commented, “Oral lichen planus is a chronic inflammatory condition that significantly impacts patients' quality of life. Traditional therapies, primarily topical corticosteroids, often lead to undesirable side effects with long-term use.
Lichen planus: Skin, mucous membranes None specific Probable 1% [16] Lichen sclerosus: Skin None specific Probable Rare [17] Linear IgA disease: Skin Anti-epidermal basement membrane IgA Confirmed Extremely rare [18] Morphea: Skin None specific Probable Not well established [19] Psoriasis: Skin Various, not specific Confirmed 2-3% [20 ...
It has mild immunosuppressive effects [1] and may displace thyroid hormone from its binding protein. [2] [3] It can also cause lichen planus. [4] Due to its side effects it was withdrawn from the UK and US in the 1980s.
Lichen planus Pterygium unguis (or dorsal pterygium [ 1 ] : 660 ) forms as a result of scarring between the proximal nailfold and matrix, with the classic example being lichen planus , though it has been reported to occur as a result of sarcoidosis and Hansen's disease .
Certain conditions, like lichen striatus (LS) and pityriasis lichenoides chronica (PLC), typically cause postinflammatory hypopigmentation as opposed to hyperpigmentation. Postinflammatory hypopigmentation can also result after cutaneous injuries caused by burns, irritants, and dermatological operations (such as chemical peels , dermabrasion ...