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Adapalene, sold under the brand name Differin among others, is a third-generation topical retinoid primarily used in the treatment of mild-moderate acne, and is also used off-label to treat keratosis pilaris as well as other skin conditions. [6] Studies have found adapalene is as effective as other retinoids, while causing less irritation. [7]
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The cold treatment not only feels good, but it helps reduce inflammation in the skin, reduce puffiness, brighten dull skin and, if you have age spots or hyperpigmentation, can help lighten those ...
Meta-analysis of clinical trials has shown this combined therapy to be more effective than either of its ingredients by themselves. [6]The use of adapalene/benzoyl peroxide in combination with oral antibiotics (lymecycline) has been studied; [7] the combination was well tolerated and showed an improved success rate compared to those receiving only antibiotics (47.6% vs. 33.7%, P = 0.002).
Synthetic retinoids are utilized in cosmetic formulations, clinical dermatology, and the treatment of some forms of cancer. [ 1 ] Retinoids have many important functions throughout the body, including in vision, [ 2 ] regulation of skin proliferation and differentiation, growth of bone tissue, immune function, [ 3 ] and male fertility.
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