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2. Biology of depression - Wikipedia

   en.wikipedia.org/wiki/Biology_of_depression

   Several theories concerning the biologically based cause of depression have been suggested over the years, including theories revolving around monoamine neurotransmitters, neuroplasticity, neurogenesis, inflammation and the circadian rhythm. Physical illnesses, including hypothyroidism and mitochondrial disease, can also trigger depressive ...

3. Disorders of diminished motivation - Wikipedia

   en.wikipedia.org/wiki/Disorders_of_diminished...

   The dopamine D 1 receptor appears to have an important role in motivation and reward. [38] Centrally acting dopamine D 1-like receptor agonists like tavapadon and razpipadon and D 1 receptor positive modulators like mevidalen and glovadalen are under development for medical use, including treatment of Parkinson's disease and notably of dementia ...

4. Feeling anxious or unhappy? Here's how to pump up your ... - AOL

   www.aol.com/lifestyle/feeling-anxious-unhappy...

   If you have low levels of dopamine, you might feel tired or unhappy, have low motivation, and could experience mood swings and concentration problems, the Cleveland Clinic says. High levels might ...

5. Neurotrophic hypothesis of depression - Wikipedia

   en.wikipedia.org/wiki/Neurotrophic_hypothesis_of...

   Depression is commonly attributed to a deficiency in monoamines, such as serotonin. The monoamine hypothesis of depression suggests that depression is primarily caused by a deficiency of several monoamines, namely serotonin, dopamine and norepinephrine. [2] This hypothesis is widely accepted due to its simplicity. [3]

6. Therapists Explain the Surprising Depression Symptoms for Men

   www.aol.com/lifestyle/therapists-explain...

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7. Late life depression - Wikipedia

   en.wikipedia.org/wiki/Late_life_depression

   Major depression is a mental disorder characterized by an all-encompassing low mood accompanied by low self-esteem, and loss of interest or pleasure in normally enjoyable activities. Nearly five million of the 31 million Americans who are 65 years or older are clinically depressed, and one million have major depression.