Search results
Results From The WOW.Com Content Network
The beta-2 adrenergic receptor (β 2 adrenoreceptor), also known as ADRB2, is a cell membrane-spanning beta-adrenergic receptor that binds epinephrine (adrenaline), a hormone and neurotransmitter whose signaling, via adenylate cyclase stimulation through trimeric G s proteins, increases cAMP, and, via downstream L-type calcium channel interaction, mediates physiologic responses such as smooth ...
Beta 2-adrenergic agonists, also known as adrenergic β 2 receptor agonists, are a class of drugs that act on the β 2 adrenergic receptor. Like other β adrenergic agonists , they cause smooth muscle relaxation. β 2 adrenergic agonists' effects on smooth muscle cause dilation of bronchial passages , vasodilation in muscle and liver ...
When NE is released into the synapse, it feeds back on the α 2 receptor, causing less NE release from the presynaptic neuron. This decreases the effect of NE. There are also α 2 receptors on the nerve terminal membrane of the post-synaptic adrenergic neuron. Actions of the α 2 receptor include: decreased insulin release from the pancreas [19]
As a result, the heart has a hard time pumping blood through the lungs, and the blood vessels eventually undergoes fibrosis. The increased workload on the heart causes hypertrophy of the right ventricle, which leads less blood being pump through the lungs and decreased blood to the left side of the heart.
If older adults have fewer attentional resources than younger adults, we would expect that when two tasks must be carried out at the same time, older adults' performance will decline more than that of younger adults. However, a large review of studies on cognition and aging suggest that this hypothesis has not been wholly supported. [56]
The cells of the neurovascular unit also make up the blood–brain barrier (BBB), which plays an important role in maintaining the microenvironment of the brain. [11] In addition to regulating the exit and entrance of blood, the blood–brain barrier also filters toxins that may cause inflammation, injury, and disease. [12]
β 2-adrenoceptor agonists are a group of drugs that act selectively on β 2-receptors in the lungs causing bronchodilation. β 2-agonists are used to treat asthma and COPD, diseases that cause obstruction in the airways. Prior to their discovery, the non-selective beta-agonist isoprenaline was used.
The myogenic mechanism is how arteries and arterioles react to an increase or decrease of blood pressure to keep the blood flow constant within the blood vessel.Myogenic response refers to a contraction initiated by the myocyte itself instead of an outside occurrence or stimulus such as nerve innervation.