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  2. Central nervous system fatigue - Wikipedia

    en.wikipedia.org/wiki/Central_Nervous_System_Fatigue

    In the brain, serotonin is a neurotransmitter and regulates arousal, behavior, sleep, and mood, among other things. [9] During prolonged exercise where central nervous system fatigue is present, serotonin levels in the brain are higher than normal physiological conditions; these higher levels can increase perceptions of effort and peripheral muscle fatigue. [9]

  3. Feeling anxious or unhappy? Here's how to pump up your ... - AOL

    www.aol.com/lifestyle/feeling-anxious-unhappy...

    Low serotonin levels have been linked to many physical and psychological symptoms, according to Healthline. However, scientists are unsure what actually causes serotonin deficiency.

  4. Fibromyalgia - Wikipedia

    en.wikipedia.org/wiki/Fibromyalgia

    The study found that low creatine and low phosphocreatine were associated with high pain, and that high stress, including PTSD, may contribute to these low levels. [72] [non-primary source needed] Low phosphocreatine levels may disrupt glutamate neurotransmission within the brains of those with fibromyalgia.

  5. Serotonin syndrome - Wikipedia

    en.wikipedia.org/wiki/Serotonin_syndrome

    The cause of serotonin toxicity or accumulation is an important factor in determining the course of treatment. Serotonin is catabolized by monoamine oxidase A in the presence of oxygen, so if care is taken to prevent an unsafe spike in body temperature or metabolic acidosis, oxygenation will assist in dispatching the excess serotonin. The same ...

  6. No ‘clear evidence’ depression is caused by low serotonin levels

    www.aol.com/no-clear-evidence-depression-caused...

    NHS figures show that the number of people in England taking antidepressants continues to rise, with 8.3m patients receiving them in 2021/22.

  7. Generalized anxiety disorder - Wikipedia

    en.wikipedia.org/wiki/Generalized_anxiety_disorder

    Lifestyle factors including: stress management, stress reduction, relaxation, sleep hygiene, and caffeine and alcohol reduction can influence anxiety levels. Physical activity has shown to have a positive impact whereas low physical activity may be a risk factor for anxiety disorders.

  8. Stress (biology) - Wikipedia

    en.wikipedia.org/wiki/Stress_(biology)

    Stress, either severe, acute stress or chronic low-grade stress may induce abnormalities in three principal regulatory systems in the body: serotonin systems, catecholamine systems, and the hypothalamic-pituitary-adrenocortical axis. Aggressive behavior has also been associated with abnormalities in these systems. [37]

  9. Serotonin - Wikipedia

    en.wikipedia.org/wiki/Serotonin

    Serotonin (/ ˌ s ɛr ə ˈ t oʊ n ɪ n, ˌ s ɪər ə-/) [6] [7] [8] or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter.Its biological function is complex, touching on diverse functions including mood, cognition, reward, learning, memory, and numerous physiological processes such as vomiting and vasoconstriction.