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CIPN afflicts between 30% and 40% of patients undergoing chemotherapy. Antineoplastic agents in chemotherapy are designed to eliminate rapidly dividing cancer cells, but they can also damage healthy structures, including the peripheral nervous system. [1] CIPN involves various symptoms such as tingling, pain, and numbness in the hands and feet. [2]
Women may also experience forms of sexual dysfunction due to damage to small blood vessels and nerves. [ 36 ] [ 37 ] Periodontal disease (gum disease): is associated with diabetes [ 38 ] Diabetes is a substantial risk factor for periodontitis, with diabetics having a threefold higher risk than non-diabetics.
Neurogenic bladder dysfunction, often called by the shortened term neurogenic bladder, refers to urinary bladder problems due to disease or injury of the central nervous system or peripheral nerves involved in the control of urination. [1] [2] There are multiple types of neurogenic bladder depending on the underlying cause and the symptoms.
Protein loss in the urine due to damage of the glomeruli may become massive, and cause a low serum albumin with resulting generalized body swelling (edema) so called nephrotic syndrome. Likewise, the estimated glomerular filtration rate (eGFR) may progressively fall from a normal of over 90 ml/min/1.73m 2 to less than 15, at which point the ...
Gemcitabine, sold under the brand name Gemzar, among others, [1] is a chemotherapy medication used to treat cancers. [2] It is used to treat testicular cancer, [3] breast cancer, ovarian cancer, non-small cell lung cancer, pancreatic cancer, and bladder cancer. [2] [4] It is administered by intravenous infusion. [2]
The most common cause of urinary retention is BPH. This disorder starts around age 50 and symptoms may appear after 10–15 years. BPH is a progressive disorder and narrows the neck of the bladder leading to urinary retention. By the age of 70, almost 10 percent of males have some degree of BPH and 33% have it by the eighth decade of life.