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2. Waldenström macroglobulinemia - Wikipedia

   en.wikipedia.org/wiki/Waldenström_macroglobulinemia

   Waldenström macroglobulinemia was first described by Jan G. Waldenström (1906–1996) in 1944 in two patients with bleeding from the nose and mouth, anemia, decreased levels of fibrinogen in the blood (hypofibrinogenemia), swollen lymph nodes, neoplastic plasma cells in bone marrow, and increased viscosity of the blood due to increased levels ...

3. Bing–Neel syndrome - Wikipedia

   en.wikipedia.org/wiki/Bing–Neel_syndrome

   Bing–Neel syndrome (BNS) is an extremely rare neurologic complication of Waldenström macroglobulinemia (WM), which is a chronic lymphoproliferative disorder. [1] There's no clear definition of BNS but what is known so far is that unlike WM, It involves the central nervous system (CNS), infiltrated by differentiated malignant B cells and by having hyperglobulinemia. [2]

4. Jan G. Waldenström - Wikipedia

   en.wikipedia.org/wiki/Jan_G._Waldenström

   Waldenström first described, in 1944, patients with a disease that has subsequently been named for him, Waldenström's macroglobulinemia, a "hyperviscosity syndrome" in which symptoms are caused by abnormal lymphocytes that prevent normal bone marrow function, which causes anemia and hepatosplenomegaly, and secrete large immunoglobulins ...

5. Bence Jones protein - Wikipedia

   en.wikipedia.org/wiki/Bence_Jones_protein

   Detection of Bence Jones protein may be suggestive of multiple myeloma, [2] or Waldenström's macroglobulinemia. [ citation needed ] Bence Jones proteins are particularly diagnostic of multiple myeloma in the context of target organ manifestations such as kidney failure , lytic (or "punched out") bone lesions, anemia , or large numbers of ...

6. Macroglobulin - Wikipedia

   en.wikipedia.org/wiki/Macroglobulin

   Waldenström macroglobulinemia is a slow-silent disease that typically develops when a person is around 65 or older, is male, has a family history of lymphoma, and is caucasian. [6] The condition is called Waldenström macroglobulinemia because the abnormal cells generate excessive levels of IgM which is the biggest immunoglobulin protein, and ...

7. Zanubrutinib - Wikipedia

   en.wikipedia.org/wiki/Zanubrutinib

   Zanubrutinib, sold under the brand name Brukinsa, is an anticancer medication used for the treatment of mantle cell lymphoma (MCL), Waldenström's macroglobulinemia (WM), marginal zone lymphoma (MZL), and chronic lymphocytic leukemia (CLL).