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The antimicrobial and antibiotic effects of macrolides, however, are not believed to be involved in their beneficial effects toward treating DPB. [13] This is evident, as the treatment dosage is much too low to fight infection, and in DPB cases with the occurrence of the macrolide-resistant bacterium Pseudomonas aeruginosa , macrolide therapy ...
Roxithromycin is a semi-synthetic macrolide antibiotic. It is used to treat respiratory tract, urinary and soft tissue infections. Roxithromycin is derived from erythromycin, containing the same 14-membered lactone ring. but with an N-oxime side chain attached to the ring. Roxithromycin was patented in 1980 and approved for medical use in 1987. [1]
Clarithromycin is an antibiotic under the class of macrolide. [33] It is indicated for the eradication of H. pylori to minimize the probability of duodenal ulcer recurrence by being a component of the combination therapy. [31] [34] Clarithromycin is available as tablets which should be taken orally. [35] [36] [37]
Common side effects include a reaction with fever, chills, ... It is a subgroup of the macrolide antibiotics, and exhibits similar structural elements. [67]
Telithromycin is the first ketolide antibiotic to enter clinical use and is sold under the brand name of Ketek. It is used to treat community acquired pneumonia of mild to moderate severity. After significant safety concerns, the US Food and Drug Administration sharply curtailed the approved uses of the drug in early 2007.
Erythromycin is a bacteriostatic macrolide antibiotic used to treat bacterial infections, ... Some of the side effects are related to vitamin A toxicity. [1] Very ...
Some drugs can inhibit CYP3A4, which means they reduce its activity and increase the blood levels of the drugs that depend on it for elimination. This can lead to adverse effects or drug-drug interactions. [47] Azithromycin is a member of macrolides that are a class of antibiotics with a cyclic structure with a lactone ring and sugar moieties ...
Spiramycin is a macrolide antibiotic and antiparasitic. It is used to treat toxoplasmosis and various other infections of soft tissues.. Although used in Europe, Canada and Mexico, [1] spiramycin is still considered an experimental drug in the United States, but can sometimes be obtained by special permission from the FDA for toxoplasmosis in the first trimester of pregnancy. [2]