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For 95–97% of cases, infection is resolved after one dose of metronidazole. [26] [35] Studies suggest that 4–5% of trichomonas cases are resistant to metronidazole, which may account for some "repeat" cases. [33] [9] Without treatment, trichomoniasis can persist for months to years in women, and is thought to improve without treatment in ...
Dosage typically includes information on the number of doses, intervals between administrations, and the overall treatment period. [3] For example, a dosage might be described as "200 mg twice daily for two weeks," where 200 mg represents the individual dose, twice daily indicates the frequency, and two weeks specifies the duration of treatment.
The 5-nitroimidazole drugs (metronidazole and tinidazole) are the mainstay of treatment for infection with Trichomonas vaginalis. Treatment for both the infected patient and the patient's sexual partner is recommended, even if asymptomatic. Therapy other than 5-nitroimidazole drugs is also an option, but cure rates are much lower. [25]
An antitrichomonal agent is an antiprotozoal agent that acts on trichomonas parasites. [1] Examples include: [2] furazolidone; nifuratel; nimorazole; ornidazole ...
Trichomoniasis is a common STI that is caused by infection with a protozoan parasite called Trichomonas vaginalis. [70] Trichomoniasis affects both women and men, but symptoms are more common in women. [71] Most patients are treated with an antibiotic called metronidazole, which is very effective. [72]
Trichomonas vaginalis from a vaginal swab. This is a heavy infection; there were probably thousands of trichomonads in the vagina. Alfred Francois Donné (1801–1878) was the first to describe a procedure to diagnose trichomoniasis through "the microscopic observation of motile protozoa in vaginal or cervical secretions" in 1836.
Threshold dose is the minimum dose of drug that triggers minimal detectable biological effect in an animal. [1] At extremely low doses, biological responses are absent for some of the drugs. The increase in dose above threshold dose induces an increase in the percentage of biological responses. [ 2 ]
Metronidazole is the treatment of choice. Treatment usually is successful after 1–2 days with early diagnosis. A new culture system called InPouch has practical advantages over the usual in vitro system. There is a risk of uncontrolled bleeding if oral plaques are removed by forceps, holding open the beak can also suffocate the bird. [11]